Evidence map›Paper›PMID 31455757›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2019

Diabetic Nephropathy versus Diabetic Retinopathy in a Chinese Population: A Retrospective Study.

Xin Cao, Xia Gong, Xiao Ma

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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  11. [Validation and comparison of diabetic retinopathy-based diagnostic models for diabetic nephropathy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Xin CaoResearch Center for Primary Health Development and General Practice Education, Jiangsu Vocational College of Medicine, Yancheng, Jiangsu, China (mainland).
Xia GongVIP Internal Medicine, The First Hospital of Lanzhou University, Lanzhou, Gansu, China (mainland).
Xiao MaDepartment of Health and Social Behavior, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China (mainland).
First Hospital of Lanzhou University · CNJiangsu Vocational College of Medicine · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND It has been reported that diabetic nephropathy and diabetic retinopathy are associated with each other through a shared pathophysiological mechanism. However, it is quite difficult to differentiate diabetic nephropathy from other glomerular diseases if diabetic retinopathy is absent in patients, and the only way to do this is to perform renal biopsies. The objective of this study was to test the hypothesis that diabetic nephropathy patients with and without diabetic retinopathy have different clinical and laboratory profiles. MATERIAL AND METHODS Medical records of type 2 diabetes mellitus patients with confirmed diabetic nephropathy were reviewed and analyzed with appropriate statistical modalities. Presence of arteriolar sclerosis of the carotid artery, abdominal aorta, upper extremities, and first-order aortic branches was regarded as a peripheral vascular disease. RESULTS Out of 217 type 2 diabetes mellitus patients with confirmed diabetic nephropathy, retinopathy was present in 106 (48.8%), while 111 (51.2%) had no evidence of retinopathy. About 45% of patients had pure diabetic nephropathy without any diagnosis of non-diabetic renal diseases, of which membranous nephropathy was most common. Diabetic nephropathy patients with retinopathy and those without retinopathy differed in duration of hypertension (p=0.041), serum creatinine (p=0.031), albumin (p=0.001), and erythrocyte sedimentation rate (p=0.001). Moreover, male preponderance (p<0.001), older age (p=0.033), and increased levels of albumin (p=0.033) were significantly associated with pure diabetic nephropathy without retinopathy. CONCLUSIONS Diabetic nephropathy patients with and without diabetic retinopathy have different clinical and laboratory profiles.

Indexed as

Asian PeopleChinaDiabetic NephropathiesDiabetic RetinopathyFemaleHumansMaleMiddle AgedPrevalenceRetrospective Studies

Identifiers

PMID31455757
PMCPMC6727671
OpenAlexW2971043931

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.