Evidence map›Paper›PMID 31455691›Full record

ArticleCancer research2019

An Activatable Cancer-Targeted Hydrogen Peroxide Probe for Photoacoustic and Fluorescence Imaging.

Judith Weber, Laura Bollepalli, Ana M Belenguer, Marco Di Antonio, Nicola De Mitri, James Joseph, Shankar Balasubramanian, Christopher A Hunter, Sarah E Bohndiek

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. The Pro-Metastatic Roles of ROS.Antioxidants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Judith WeberCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
Laura BollepalliCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-5902-059X
Ana M BelenguerDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-0443-4856
Marco Di AntonioDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-7321-1867
Nicola De MitriDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-7127-9585
James JosephCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-6270-2559
Shankar BalasubramanianCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-0281-5815
Christopher A HunterDepartment of Chemistry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-5182-1859
Sarah E BohndiekCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom. seb53@cam.ac.uk.
University of Cambridge · GB

Funding

Cancer Research UK 16267Cancer Research UK 16465Cancer Research UK 18618Cancer Research UK 21142Cancer Research UK A16267Cancer Research UK A16465
6 · The paper itself

Abstract

Reactive oxygen species play an important role in cancer, however, their promiscuous reactivity, low abundance, and short-lived nature limit our ability to study them in real time in living subjects with conventional noninvasive imaging methods. Photoacoustic imaging is an emerging modality for

Indexed as

Absorption, RadiationAdenocarcinomaAnimalsCell Line, TumorDeoxyglucoseFluorescent DyesHeterograftsHumansHydrogen PeroxideLiver NeoplasmsMCF-7 CellsMiceMice, NudeMolecular ImagingNeoplasm TransplantationOptical ImagingDeoxyglucoseFluorescent DyesHydrogen PeroxidePiperazines

Identifiers

PMID31455691
PMCPMC7611383
OpenAlexW2970279980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.