Evidence map›Paper›PMID 31455636›Full record

ArticleThe Journal of biological chemistry2019

An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine.

Jinyu Yin, Yifeng Wei, Dazhi Liu, Yiling Hu, Qiang Lu, Ee Lui Ang, Huimin Zhao, Yan Zhang

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  5. Article
  6. An aldolase-dependent phloroglucinol degradation pathway inApplied and environmental microbiology · 2024
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinyu YinTianjin Key Laboratory for Modern Drug Delivery and High Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Yifeng WeiMetabolic Engineering Research Laboratory, Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Dazhi LiuTianjin Key Laboratory for Modern Drug Delivery and High Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Yiling HuTianjin Key Laboratory for Modern Drug Delivery and High Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Qiang LuTianjin Key Laboratory for Modern Drug Delivery and High Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Ee Lui AngMetabolic Engineering Research Laboratory, Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Huimin ZhaoMetabolic Engineering Research Laboratory, Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore zhao5@illinois.edu.ORCID 0000-0002-9069-6739
Yan ZhangTianjin Key Laboratory for Modern Drug Delivery and High Efficiency, Collaborative Innovation Center of Chemical Science and Engineering, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China yan.zhang@tju.edu.cn.ORCID 0000-0003-2031-0631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reductive pyrimidine catabolic pathway is the most widespread pathway for pyrimidine degradation in bacteria, enabling assimilation of nitrogen for growth. This pathway, which has been studied in several bacteria including

Indexed as

Metabolic Networks and PathwaysBacillaceaeBacterial Proteinsbeta-AlanineBiocatalysisKineticsMultigene FamilyNitrogenPyrimidinesRecombinant ProteinsUracilBacterial Proteinsbeta-AlanineNitrogenpyrimidinePyrimidinesRecombinant ProteinsUracil2-oxoglutarate3-hydroxypropionateaminotransferasebeta-alanineenzyme kineticsenzyme phylogenymalonic semialdehyde reductasenitrogen assimilationnitrogen metabolismpyridoxal phosphatepyrimidinereductasereductive pathway

Identifiers

PMID31455636
PMCPMC6816092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.