Evidence map›Paper›PMID 31455418›Full record

ReviewBiological research2019

Molecular aspects of the teratogenesis of rubella virus.

Suji George, Rajlakshmi Viswanathan, Gajanan N Sapkal

Open access · goldAbstract readReview
In one paragraph

Review in Biological research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Bee products as alternatives in the treatment of viral infections.Journal of the science of food and agriculture · 2026
    Review
  2. Article
  3. Review
  4. Fundus imaging features of congenital rubella retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  5. Article
  6. SiScience · 2023
    Article
  7. MaternalFrontiers in cellular neuroscience · 2023
    Article
  8. Article
  9. Article
  10. Revisiting Regulated Cell Death Responses in Viral Infections.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Rubella Immunity among Italian Female Healthcare Workers: A Serological Study.International journal of environmental research and public health · 2020
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Suji GeorgeDiagnostic Virology Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Rajlakshmi ViswanathanDiagnostic Virology Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India.
Gajanan N SapkalDiagnostic Virology Group, ICMR-National Institute of Virology, 20-A, Dr. Ambedkar Road, Pune, Maharashtra, 411001, India. gajanansapkalniv@gmail.com.ORCID http://orcid.org/0000-0001-9283-8860
ICMR-National Institute of Virology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rubella or German measles is an infection caused by rubella virus (RV). Infection of children and adults is usually characterized by a mild exanthematous febrile illness. However, RV is a major cause of birth defects and fetal death following infection in pregnant women. RV is a teratogen and is a major cause of public health concern as there are more than 100,000 cases of congenital rubella syndrome (CRS) estimated to occur every year. Several lines of evidence in the field of molecular biology of RV have provided deeper insights into the teratogenesis process. The damage to the growing fetus in infected mothers is multifactorial, arising from a combination of cellular damage, as well as its effect on the dividing cells. This review focuses on the findings in the molecular biology of RV, with special emphasis on the mitochondrial, cytoskeleton and the gene expression changes. Further, the review addresses in detail, the role of apoptosis in the teratogenesis process.

Indexed as

TeratogenesisApoptosisCongenital AbnormalitiesFemaleHumansMitochondriaPregnancyPregnancy Complications, InfectiousRubellaRubella Syndrome, CongenitalRubella virusSignal TransductionVirus ReplicationApoptosisMitochondriaRubellaTeratogenesis

Identifiers

PMID31455418
PMCPMC6712747
OpenAlexW2970587095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.