Evidence map›Paper›PMID 31455399›Full record

ArticleJournal of orthopaedic surgery and research2019

Active unicameral bone cysts: control firstly, cure secondly.

Qing Liu, Hongbo He, Hao Zeng, Yuhao Yuan, Zhiwei Wang, Xiaopeng Tong, Wei Luo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qing LiuDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Hongbo HeDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Hao ZengDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Yuhao YuanDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Zhiwei WangDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Xiaopeng TongDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Wei LuoDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, China. luowei0928@126.com.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

the Clinical and Rehabilitation Research Foundation of Xiangya Hospital and Weiming of Peking University xywm2015II07the Fundamental Research Funds for the Central Universities of Central South University 2019zzts019 and 2019zzts809the Key Scientific Research and Innovation Projects of Hunan Postgraduates CX20190074the Provincial Science Foundation of Hunan 2017JJ3499the Research project of Hunan health and Family Planning Commission C20180785
6 · The paper itself

Abstract

purposeThis retrospective study evaluated the efficacy of minimally invasive surgery to control cyst progression for active unicameral bone cysts (AUBC) by intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting.

methodsFrom May 2010 to May 2017, patients diagnosed with AUBC who underwent percutaneous double-needle intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting were retrospectively reviewed. Recurrence was defined by modified Neer scale score. Patients were followed up regularly, and previous imaging findings were compared to evaluate treatment efficacy.

resultsThe 26 patients (17 boys, 9 girls, mean age, 9.4 ± 3.1 years) were followed up for a mean 45.1 months (range, 24-82 months). Follow-up consisted of clinical evaluation and radiographic review. Twenty patients (77%) achieved latent disease stage after the first treatment, while six (23%) achieved it after the second treatment. Postoperative pathological fracture imaging scores were score I in 18 (70%), score II in five (19%), score III in two (8%), and score IV in one patient (4%). All 26 patients returned to their full activities and were asymptomatic at the most recent follow-up. The success rate (scores I and II) independent of the number of treatments was 89%. Treatment time was correlated with cyst size and length. Sex, age, cyst location and size, pathological fracture, and other clinical factors or radiological data did not influence the curative effect. No other complications occurred.

conclusionsFor AUBC, minimally invasive treatment is feasible to control cyst progression and then cure it without sequelae. Intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting are an excellent choice.

Indexed as

Bone CystsChildFemaleFollow-Up StudiesHumansMaleMinimally Invasive Surgical ProceduresRetrospective StudiesAutogenous bone marrow graftingIntracystic methylprednisolone injectionPercutaneous curettageUnicameral bone cysts

Identifiers

PMID31455399
PMCPMC6712734
OpenAlexW2970659940

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.