Evidence map›Paper›PMID 31455387›Full record

ArticleGenome biology2019

Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes.

Kunhee Kim, Hyungryul Baik, Chloe Soohyun Jang, Jin Kyung Roh, Eleazer Eskin, Buhm Han

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Maternal obesity and ancestry distance in influencing birth outcomes.International journal of obesity (2005) · 2025
    Observational
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kunhee KimDepartment of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan College of Medicine, Seoul, South Korea.
Hyungryul BaikDepartment of Mathematical Science, KAIST, Daejeon, South Korea.
Chloe Soohyun JangDepartment of Medical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Jin Kyung RohDepartment of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Eleazer EskinDepartment of Computer Science and Human Genetics, University of California Los Angeles, Los Angeles, CA, USA.
Buhm HanDepartment of Medical Sciences, Seoul National University College of Medicine, Seoul, South Korea. buhm.han@snu.ac.kr.ORCID 0000-0002-2266-5164

Funding

Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
Integrative Center for Neurogenetics and Neurogenomics - OverallP30NS062691 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COPPOLA, GIOVANNI, FREIMER, NELSON B. · 2009 to 2018
$7.4M
National Institute of Neurological Disorders and Stroke (US) P30NS062691NIH HHS K25-HL080079, U01-DA024417, P01-HL30568, P01-HL28481, R01-GM083198, R01-ES021801, R01-MH101782 and R01-ES022282NIH HHS U54EB020403
6 · The paper itself

Abstract

Genomic global positioning system (GPS) applies the multilateration technique commonly used in the GPS to genomic data. In the framework we present here, investigators calculate genetic distances from their samples to reference samples, which are from data held in the public domain, and share this information with others. This sharing enables certain types of genomic analysis, such as identifying sample overlaps and close relatives, decomposing ancestry, and mapping of geographical origin without disclosing personal genomes. Thus, our method can be seen as a balance between open data sharing and privacy protection.

Indexed as

Databases, GeneticGenome, HumanGenetics, PopulationGenomicsHumansData sharingGenetic distanceMultilaterationPersonal genomePrivacy protection

Identifiers

PMID31455387
PMCPMC6712716

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.