ArticleBMC public health2019
Severity of depression, anxious distress and the risk of type 2 diabetes - a population-based cohort study in Sweden.
Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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18 citing papers in PubMed.
- Effect of omega-3 and vitamin D co-supplementation on psychological distress in reproductive-aged women with pre-diabetes and hypovitaminosis D: A randomized controlled trial.Brain and behavior · 2021Trial
- High plasma levels of soluble triggering receptor expressed on Myeloid Cells 2 were associated with depression in patients with newly diagnosed type 2 diabetes mellitus.Journal of clinical & translational endocrinology · 2026Article
- Observational
- New-onset mental disorders increase among patients with metabolic diseases after the COVID-19 pandemic.Scientific reports · 2025Observational
- Structural analysis of social behavior: Using cluster analysis to examine personality profile associated with diabetes onset.PloS one · 2025Article
- Abnormalities of lipid metabolism in the progression and treatment of depression.Frontiers in psychiatry · 2025Review
- Change in mental health service utilization from pre- to post-COVID-19 period in the United States.Heliyon · 2024Article
- A modified persian version of the self-stigma of depression scale among the Iranian population: a methodological study in 2023.BMC psychology · 2024Article
- Article
- Comparing sodium-glucose cotransporter 2 inhibitors and dipeptidyl peptidase-4 inhibitors on new-onset depression: a propensity score-matched study in Hong Kong.Acta diabetologica · 2023Article
- Depression was associated with younger age, female sex, obesity, smoking, and physical inactivity, in 1027 patients with newly diagnosed type 2 diabetes: a Swedish multicentre cross-sectional study.BMC endocrine disorders · 2022Article
- Traditional Chinese Medicine Body Constitutions as Predictors for Depression: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2022Review
- Depressive symptoms and allostatic load have a bidirectional association among Puerto Rican older adults.Psychological medicine · 2022Article
- The association between type 2 diabetes and major depression in apnoeic individuals.Sleep and biological rhythms · 2022Article
- Informal care and the impact on depression and anxiety among Swedish adults: a population-based cohort study.BMC public health · 2021Article
- Association Between Psychological Distress and Stress-Related Symptoms and Increased Risk of Type 2 Diabetes in Male Individuals: An Observational Study.Journal of clinical medicine research · 2020Article
- Correction to: Severity of depression, anxious distress and the risk of type 2 diabetes - a population-based cohort study in Sweden.BMC public health · 2019Article
- Depression Exacerbates Hepatic Steatosis in C57BL/6J Mice by Activating the Hypothalamic-Pituitary-Adrenal Axis.In vivo (Athens, Greece)Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
backgroundPrevious studies assessing the relationship between depression and diabetes mellitus did not consider the severity of depression. In the present study we assessed the risk of developing type 2 diabetes mellitus (T2DM) among people with various severity of depression.
methodsThis prospective longitudinal cohort study included 9,936 individuals residing in Stockholm County, Sweden who responded to the baseline questionnaire in 1998-2000. The participants were followed from 1 year after the baseline up to 2015 for the occurrence of T2DM, using the National Patient Register, Swedish Prescribed Drug Registers, and Cause of Death Register. Depression and anxious distress were assessed using psychiatric rating scales and defined according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).
resultsDepression was associated with a statistically significant increased risk of T2DM after adjusting for potential confounders (OR 1.48, CI 1.10, 1.99). The strongest association was observed for severe depression (OR 1.72, CI 1.15, 2.59). Further, those with depression, regardless of severity, and with concurrent moderate/severe anxious distress had an increased risk of T2DM (OR 1.73, CI 1.13, 2.63) compared to those with neither depression nor anxious distress.
conclusionsThe study adds evidence that depression is associated with a higher risk for developing T2DM, and the association is stronger among people with severe depression.
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