Evidence map›Paper›PMID 31455290›Full record

ArticleBMC public health2019

Self-harm in young people with perinatal HIV and HIV negative young people in England: cross sectional analysis.

Julie Copelyn, Lindsay C Thompson, Marthe Le Prevost, Hannah Castro, Kate Sturgeon, Katie Rowson, Susie Brice, Caroline Foster, Diana M Gibb, Ali Judd and 1 more

Abstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julie CopelynMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Lindsay C ThompsonMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Marthe Le PrevostMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Hannah CastroMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Kate SturgeonMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Katie RowsonMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Susie BriceMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Caroline FosterImperial College Healthcare NHS Trust, London, UK.
Diana M GibbMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK.
Ali JuddMedical Research Council (MRC) Clinical Trials Unit at University College London (UCL), 90 High Holborn, WC1V 6LJ, London, UK. a.judd@ucl.ac.uk.ORCID http://orcid.org/0000-0003-3176-5295
Adolescents and Adults Living with Perinatal HIV (AALPHI) Steering Committee

Funding

Medical Research Council G9815508Medical Research Council MC_PC_19009Medical Research Council MC_UU_12023/17Medical Research Council MC_UU_12023/26
6 · The paper itself

Abstract

backgroundSelf-harm in adolescents is of growing concern internationally but limited evidence exists on the prevalence of self-harm in those living with HIV, who may be at higher risk of poor mental health outcomes. Therefore our aim was to determine the prevalence and predictors of self-harm among young people with perinatally-acquired HIV (PHIV) and HIV negative (with sibling or mother living with HIV) young people living in England.

methods303 PHIV and 100 HIV negative young people (aged 12-23 years) participating in the Adolescents and Adults Living with Perinatal HIV cohort study completed an anonymous self-harm questionnaire, as well as a number of standardised mental-health assessments. Logistic regression investigated predictors of self-harm.

resultsThe median age was 16.7 years in both groups, and 40.9% of the PHIV and 31.0% of the HIV negative groups were male. In total 13.9% (56/403) reported having ever self-harmed, with no difference by HIV status (p = 0.089). Multivariable predictors of self-harm were female sex (adjusted odds ratio (AOR) 5.3, (95% confidence interval 1.9, 14.1), p = 0.001), lower self-esteem (AOR 0.9 (0.8, 0.9) per 1 point increase, p < 0.001) and having ever used alcohol (AOR 3.8 (1.8, 7.8), p < 0.001). Self-esteem z-scores for both PHIV and HIV negative participants were 1.9 standard deviations below the mean for population norms.

conclusionsSelf-harm is common among PHIV and HIV negative adolescents in England. Reassuringly however, they do not appear to be at an increased risk compared to the general adolescent population (15-19% lifetime prevalence). The low level of self-esteem (compared to available normative data) in both groups is worrying and warrants further attention.

Indexed as

AdolescentChildCohort StudiesCross-Sectional StudiesEnglandFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMalePrevalenceRisk FactorsSelf ConceptSelf-Injurious BehaviorSurveys and QuestionnairesYoung AdultAdolescentsEnglandHIVPerinatalSelf-esteemSelf-harmYoung people

Identifiers

PMID31455290
PMCPMC6712658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.