Evidence map›Paper›PMID 31455261›Full record

ReviewBMC infectious diseases2019

Cerebral sparganosis presenting with atypical postcontrast magnetic resonance imaging findings: a case report and literature review.

Yueli Zhu, Lingqi Ye, Xiansan Ding, Jimin Wu, Yanxing Chen

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. The clinical, neuroradiological, and pathological features of cerebral sparganosis in Jiangxi Province, China.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
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  9. Article
  10. Epidemiology, Diagnosis, and Prevention of Sparganosis in Asia.Animals : an open access journal from MDPI · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yueli ZhuDepartment of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lingqi YeDepartment of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xiansan DingDepartment of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jimin WuDepartment of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yanxing ChenDepartment of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. chenyanxing@zju.edu.cn.
Second Affiliated Hospital of Zhejiang University · CN

Funding

National Natural Science Foundation of China (CN) 81870826Natural Science Foundation of Zhejiang Province (CN) LY18H090004
6 · The paper itself

Abstract

backgroundSparganosis, a rare and severe parasitic infection caused by the larvae of Spirometra species or simply sparganum, generally involves subcutaneous tissue or muscle. But occasionally, sparganum can also invade the human brain, resulting in cerebral sparganosis. CASE PRESENTATION: A 33-year-old woman presented with a 10-day history of headache. Postcontrast magnetic resonance imaging (MRI) revealed an irregular lesion with enhancement and the tunnel-shaped focus extending to the contralateral hemiphere. Cerebrospinal fluid (CSF) analysis disclosed pleocytosis (166 cells/μL) and an elevated protein concentration (0.742 g/L). Enzyme-linked immunosorbent assay (ELISA) revealed positive sparganum-specific antibody in both blood and CSF. Finally, the diagnosis of cerebral sparganosis was comfirmed. She received praziquantel treatment and got a favorable outcome during six-month follow-up.

conclusionsIrregular enhancement and the tunnel sign that extends to the contralateral hemisphere on postconstrast MRI are unusual presentations of cerebral sparganosis. ELISA for sparganum-specific antibody can help confirm the diagnosis. Although surgery is the preferred treatment for cerebral sparganosis, praziquantel might also achieve satisfying outcomes.

Indexed as

AdultAnimalsAnthelminticsAntibodies, HelminthBrain DiseasesCerebrospinal FluidContrast MediaEnzyme-Linked Immunosorbent AssayFemaleHeadacheHumansMagnetic Resonance ImagingPraziquantelSparganosisSpirometraAnthelminticsAntibodies, HelminthContrast MediaPraziquantelCerebral sparganosisELISAPraziquantelTunnel sign

Identifiers

PMID31455261
PMCPMC6712767
OpenAlexW2970671173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.