Evidence map›Paper›PMID 31455228›Full record

ArticleBMC bioinformatics2019

Reverse active learning based atrous DenseNet for pathological image classification.

Yuexiang Li, Xinpeng Xie, Linlin Shen, Shaoxiong Liu

Abstract read
In one paragraph

Article in BMC bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

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13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  6. Eyebirds: Enabling the Public to Recognize Water Birds at Hand.Animals : an open access journal from MDPI · 2022
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yuexiang LiComputer Vision Institute, College of Computer Science and Software Engineering, Shenzhen University, Shenzhen, China.
Xinpeng XieComputer Vision Institute, College of Computer Science and Software Engineering, Shenzhen University, Shenzhen, China.
Linlin ShenComputer Vision Institute, College of Computer Science and Software Engineering, Shenzhen University, Shenzhen, China. llshen@szu.edu.cn.ORCID http://orcid.org/0000-0003-1420-0815
Shaoxiong LiuThe Sixth People's Hospital of Shenzhen, Shenzhen, China.

Funding

National Natural Science Foundation of China 61672357National Natural Science Foundation of China 61702339 and U1713214Science and Technology Project of Guangdong Province 2018A050501014
6 · The paper itself

Abstract

backgroundDue to the recent advances in deep learning, this model attracted researchers who have applied it to medical image analysis. However, pathological image analysis based on deep learning networks faces a number of challenges, such as the high resolution (gigapixel) of pathological images and the lack of annotation capabilities. To address these challenges, we propose a training strategy called deep-reverse active learning (DRAL) and atrous DenseNet (ADN) for pathological image classification. The proposed DRAL can improve the classification accuracy of widely used deep learning networks such as VGG-16 and ResNet by removing mislabeled patches in the training set. As the size of a cancer area varies widely in pathological images, the proposed ADN integrates the atrous convolutions with the dense block for multiscale feature extraction.

resultsThe proposed DRAL and ADN are evaluated using the following three pathological datasets: BACH, CCG, and UCSB. The experiment results demonstrate the excellent performance of the proposed DRAL + ADN framework, achieving patch-level average classification accuracies (ACA) of 94.10%, 92.05% and 97.63% on the BACH, CCG, and UCSB validation sets, respectively.

conclusionsThe DRAL + ADN framework is a potential candidate for boosting the performance of deep learning models for partially mislabeled training datasets.

Indexed as

Deep LearningImage Processing, Computer-AssistedAlgorithmsDatabases as TopicHumansModels, TheoreticalNeoplasmsReproducibility of ResultsActive learningAtrous convolutiondeep learningPathological image classification

Identifiers

PMID31455228
PMCPMC6712615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.