Evidence map›Paper›PMID 31455205›Full record

ArticleBMC molecular and cell biology2019

Improved homology modeling of the human & rat EP

Melissa C Holt, Chi S Ho, M Inés Morano, Stephen D Barrett, Adam J Stein

Open access · goldAbstract read
In one paragraph

Article in BMC molecular and cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Alkyne migratory functionalization via C(spNature communications · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Melissa C HoltCayman Chemical Co, 1180 E. Ellsworth Rd, Ann Arbor, MI, 48108, USA.
Chi S HoCayman Chemical Co, 1180 E. Ellsworth Rd, Ann Arbor, MI, 48108, USA.
M Inés MoranoCayman Chemical Co, 1180 E. Ellsworth Rd, Ann Arbor, MI, 48108, USA.
Stephen D BarrettCayman Chemical Co, 1180 E. Ellsworth Rd, Ann Arbor, MI, 48108, USA.
Adam J SteinCayman Chemical Co, 1180 E. Ellsworth Rd, Ann Arbor, MI, 48108, USA. astein@caymanchem.com.ORCID 0000-0002-9948-0870
Cayman Chemical (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe EP

resultsRank-ordering of in silico compound docking scores aligned well with in vitro activity assay EC

conclusionsThis work has generated a set of novel homology models of the rEP

Indexed as

Models, MolecularStructural Homology, ProteinAmino Acid SequenceAnimalsDecapodiformesDinoprostoneHumansLigandsMolecular Docking SimulationRatsReceptors, Prostaglandin E, EP4 SubtypeRhodopsinDinoprostoneLigandsReceptors, Prostaglandin E, EP4 SubtypeRhodopsinsulprostoneBone healingEP4Heart failureHomology modelPGE2Prostaglandin E2Prostaglandin E2 receptorProstaglandin E2 receptor subtype 4Structure-based drug design

Identifiers

PMID31455205
PMCPMC6712885
OpenAlexW2971248510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.