ArticleCartilage2021
A New Method for Cartilage Evaluation in Femoroacetabular Impingement Using Quantitative T2 Magnetic Resonance Imaging: Preliminary Validation against Arthroscopic Findings.
Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Diagnostic and prognostic potential of biomarkers in femoroacetabular impingement syndrome: A systematic review.Journal of experimental orthopaedics · 2025Review
- TJournal of magnetic resonance imaging : JMRI · 2025Article
- Current understanding of articular cartilage lesions in femoroacetabular impingement syndrome.Journal of orthopaedic surgery and research · 2024Review
- Automated quantification of cartilage quality for hip treatment decision support.International journal of computer assisted radiology and surgery · 2022Article
- Correcting for imaging gradients-related bias of TMagnetic resonance in medicine · 2022Article
- Determining the internal orientation, degree of ordering, and volume of elongated nanocavities by NMR: Application to studies of plant stem.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- Quantification of Intra-Muscular Adipose Infiltration in Calf/Thigh MRI Using Fully and Weakly Supervised Semantic Segmentation.Bioengineering (Basel, Switzerland) · 2022Article
- Post-Run TCartilage · 2021Article
- Efficient TMagnetic resonance in medicine · 2021Article
- Complications of hip preserving surgery.EFORT open reviews · 2021Review
- Hip preservation.EFORT open reviews · 2020Review
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Authors and funding
6 authors.
Funding
Abstract
objectiveThe outcome of arthroscopic treatment for femoroacetabular impingement (FAI) depends on the preoperative status of the hip cartilage. Quantitative T2 can detect early biochemical cartilage changes, but its routine implementation is challenging. Furthermore, intrinsic T2 variability between patients makes it difficult to define a threshold to identify cartilage lesions. To address this, we propose a normalized T2-index as a new method to evaluate cartilage in FAI.
designWe retrospectively analyzed magnetic resonance imaging (MRI) data of 18 FAI patients with arthroscopically confirmed cartilage defects. Cartilage T2 maps were reconstructed from multi-spin-echo 3-T data using the echo-modulation-curve (EMC) model-based technique. The central femoral cartilage, assumed healthy in early-stage FAI, was used as the normalization reference to define a T2-index. We investigated the ability of the T2-index to detect surgically confirmed cartilage lesions.
resultsThe average T2-index was 1.14 ± 0.1 and 1.13 ± 0.1 for 2 separated segmentations. Using T2-index >1 as the threshold for damaged cartilage, accuracy was 88% and 100% for the 2 segmentations. We found moderate intraobserver repeatability, although separate segmentations yielded comparable accuracy. Damaged cartilage could not be identified using nonnormalized average T2 values.
conclusionsThis preliminary study confirms the importance of normalizing T2 values to account for interpatient variability and suggests that the T2-index is a promising biomarker for the detection of cartilage lesions in FAI. Future work is needed to confirm that combining T2-index with morphologic MRI and other quantitative biomarkers could improve cartilage assessment in FAI.
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