Evidence map›Paper›PMID 31454903›Full record

ArticleMethods and protocols2019

An Assay to Study Intra-Chromosomal Deletions in Yeast.

Bailey E Lucas, Matthew T McPherson, Tila M Hawk, Lexia N Wilson, Jacob M Kroh, Kyle G Hickman, Sean R Fitzgerald, W Miguel Disbennett, P Daniel Rollins, Hannah M Hylton and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods and protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Expression of EndonucleaseCurrent issues in molecular biology · 2026
    Article
  2. Genetic interaction of the histone chaperonemicroPublication biology · 2022
    Article
  3. Genes · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Bailey E LucasDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Matthew T McPhersonDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Tila M HawkDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Lexia N WilsonDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.ORCID 0000-0001-8924-3751
Jacob M KrohDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Kyle G HickmanDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Sean R FitzgeraldDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
W Miguel DisbennettMicrobiology Program, The Ohio State University, Columbus, OH 43210, USA.
P Daniel RollinsMolecular Genetics Program, The Ohio State University, Columbus, OH 43210, USA.
Hannah M HyltonDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Mohammed A BaseerDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Paige N MontgomeryDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA.
Jian-Qiu WuDepartment of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA.
Ruben C PetreacaDepartment of Molecular Genetics, The Ohio State University, Marion, OH 43302, USA. petreaca.1@osu.edu.
The Ohio State University at Marion · USThe Ohio State University · US

Funding

Development of a Novel Genetic Assay to Study DNA Double Strand BreaksR03CA223545 · NCI · OHIO STATE UNIVERSITY · PI PETREACA, RUBEN CIPRIAN · 2018 to 2019
$156k
NCI NIH HHS R03 CA223545NIH HHS RO3 CA223545-01
6 · The paper itself

Abstract

An accurate DNA damage response pathway is critical for the repair of DNA double-strand breaks. Repair may occur by homologous recombination, of which many different sub-pathways have been identified. Some recombination pathways are conservative, meaning that the chromosome sequences are preserved, and others are non-conservative, leading to some alteration of the DNA sequence. We describe an in vivo genetic assay to study non-conservative intra-chromosomal deletions at regions of non-tandem direct repeats in

Indexed as

DNA double-strand breaksGenetic RecombinationYeast

Identifiers

PMID31454903
PMCPMC6789737
OpenAlexW2971169574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.