Evidence map›Paper›PMID 31454892›Full record

ArticleInternational journal of molecular sciences2019

SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers.

Fabia Fricke, Malwina Michalak, Uwe Warnken, Ingrid Hausser, Martina Schnölzer, Jürgen Kopitz, Johannes Gebert

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  12. Inter-Laboratory Comparison of Extracellular Vesicle Isolation Based on Ultracentrifugation.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2021
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  16. Molecular and Translational Research on Colorectal Cancer.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fabia FrickeDepartment Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.ORCID 0000-0001-5629-4368
Malwina MichalakDepartment Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
Uwe WarnkenFunctional Proteome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.
Ingrid HausserEM-Lab, Institute of Pathology, Im Neuenheimer Feld 224, Heidelberg University Hospital, 69120 Heidelberg, Germany.ORCID 0000-0002-1095-4962
Martina SchnölzerFunctional Proteome Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.
Jürgen KopitzDepartment Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.
Johannes GebertDepartment Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany. johannes.gebert@med.uni-heidelberg.de.
German Cancer Research Center · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microsatellite unstable (MSI) colorectal cancers (CRCs) are characterized by mutational inactivation of

Indexed as

Biological AssayMicrosatellite InstabilityAmino AcidsCell Line, TumorColorectal NeoplasmsExtracellular VesiclesGene Expression Regulation, NeoplasticHumansIsotope LabelingProtein BiosynthesisProtein Interaction MappingProtein Interaction MapsReceptor, Transforming Growth Factor-beta Type IIReproducibility of ResultsAmino AcidsReceptor, Transforming Growth Factor-beta Type IITGFBR2 protein, humancolorectal cancerDNA mismatch repairexosomesextracellular vesiclesmicrosatellite instabilityproteomicsstable isotope labeling with amino acids in cell culture (SILAC)TGFBR2

Identifiers

PMID31454892
PMCPMC6747473
OpenAlexW2969412263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.