Evidence map›Paper›PMID 31454882›Full record

ArticleInternational journal of molecular sciences2019

Local Growth Hormone Therapy for Pressure Ulcer Healing on a Human Skin Mouse Model.

Lara Cristóbal, Nerea de Los Reyes, Miguel A Ortega, Melchor Álvarez-Mon, Natalio García-Honduvilla, Julia Buján, Andrés A Maldonado

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Hormonal interventions in skin wounds - a mini review.Molecular medicine (Cambridge, Mass.) · 2024
    Review
  3. Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Growth Hormone and the Human Hair Follicle.International journal of molecular sciences · 2021
    Review
  8. Observational
  9. Wound Repair and Regeneration: Mechanisms, Signaling.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lara CristóbalDepartment of Plastic and Reconstructive Surgery and Burn Unit. University Hospital of Getafe, 28905 Madrid, Spain.
Nerea de Los ReyesDepartment of Plastic and Reconstructive Surgery and Burn Unit. University Hospital of Getafe, 28905 Madrid, Spain.
Miguel A OrtegaDepartment of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Madrid, Spain.
Melchor Álvarez-MonDepartment of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Madrid, Spain.
Natalio García-HonduvillaDepartment of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Madrid, Spain.
Julia BujánDepartment of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Madrid, Spain.
Andrés A MaldonadoDepartment of Medicine and Medical Specialties, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Madrid, Spain. mail@andresmaldonado.es.ORCID 0000-0002-3703-5667
Universidad de Alcalá · ESHospital Universitario de Getafe · ES

Funding

Consejería de Educación e Investigación B2017/BMD-3804 MITIC-CMFundación Mapfre SA/11/AYU/444
6 · The paper itself

Abstract

The growth hormone is involved in skin homeostasis and wound healing. We hypothesize whether it is possible to improve pressure ulcer (PU) healing by locally applying the recombinant human growth hormone (rhGH) in a human skin mouse model. Non-obese diabetic/severe combined immunodeficient mice (

Indexed as

AnimalsBiomarkersBiopsyCollagenDisease Models, AnimalGrowth HormoneHuman Growth HormoneHumansMaleMicePressure UlcerRecombinant ProteinsSkinSkin TransplantationWound HealingBiomarkersCollagenGrowth HormoneHuman Growth HormoneRecombinant Proteinsgrowth hormonehuman skin graftpressure ulcer treatmentwound healing

Identifiers

PMID31454882
PMCPMC6747216
OpenAlexW2969943288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.