Evidence map›Paper›PMID 31454370›Full record

ArticlePloS one2019

Immigration and establishment of Trypanosoma cruzi in Arequipa, Peru.

Alexander S F Berry, Renzo Salazar-Sánchez, Ricardo Castillo-Neyra, Katty Borrini-Mayorí, Claudia Chipana-Ramos, Melina Vargas-Maquera, Jenny Ancca-Juarez, César Náquira-Velarde, Michael Z Levy, Dustin Brisson and 1 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Use of a Latent Class Analysis in the Diagnosis of Chronic Chagas Disease in the Washington Metropolitan Area.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  5. Article
  6. Dispersal patterns of Trypanosoma cruzi in Arequipa, Peru.PLoS neglected tropical diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander S F BerryDivision of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States of America.ORCID 0000-0003-0353-5521
Renzo Salazar-SánchezUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.ORCID 0000-0002-5127-0479
Ricardo Castillo-NeyraUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.
Katty Borrini-MayoríUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.ORCID 0000-0003-3134-7069
Claudia Chipana-RamosUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.
Melina Vargas-MaqueraUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.
Jenny Ancca-JuarezUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.
César Náquira-VelardeUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.ORCID 0000-0003-0271-4165
Michael Z LevyUniversidad Peruana Cayetano Heredia/University of Pennsylvania Zoonotic Disease Research Laboratory, Arequipa, Peru.
Dustin BrissonDepartment of Biology, University of Pennsylvania, Philadelphia, PA, United States of America.ORCID 0000-0002-9493-7579
Chagas Disease Working Group in Arequipa

Funding

Training Program in Computational GenomicsT32HG000046 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI JUNHYONG KIM, Mingyao Li · 1999 to 2026
$9.5M
PARASITOLOGY: MODERN APPROACHEST32AI007532 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 1998 to 2022
$5.0M
Disrupting Vector-borne Disease Transmission in Complex Urban EnvironmentsR01AI101229 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LEVY, MICHAEL Z · 2013 to 2017
$3.1M
Phylogeographic dynamics of tick-borne pathogensR01AI142572 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BRISSON, DUSTIN · 2018 to 2023
$2.4M
Phylogeographic dynamics of a vector and pathogen in a natural environmentR01AI097137 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BRISSON, DUSTIN · 2012 to 2016
$1.9M
NHGRI NIH HHS T32 HG000046NIAID NIH HHS R01 AI097137NIAID NIH HHS R01 AI101229NIAID NIH HHS R01 AI142572NIAID NIH HHS T32 AI007532
6 · The paper itself

Abstract

Changing environmental conditions, including those caused by human activities, reshape biological communities through both loss of native species and establishment of non-native species in the altered habitats. Dynamic interactions with the abiotic environment impact both immigration and initial establishment of non-native species into these altered habitats. The repeated emergence of disease systems in urban areas worldwide highlights the importance of understanding how dynamic migratory processes affect the current and future distribution and abundance of pathogens in urban environments. In this study, we examine the pattern of invasion of Trypanosoma cruzi-the causative agent of human Chagas disease-in the city of Arequipa, Peru. Phylogenetic analyses of 136 T. cruzi isolates from Arequipa and other South American locations suggest that only one T. cruzi lineage established a population in Arequipa as all T. cruzi isolated from vectors in Arequipa form a recent monophyletic group within the broader South American phylogeny. We discuss several hypotheses that may explain the limited number of established T. cruzi lineages despite multiple introductions of the parasite.

Indexed as

Emigration and ImmigrationChagas DiseaseGeographyHumansPeruPhylogenyPolymorphism, Single NucleotideTrypanosoma cruzi

Identifiers

PMID31454370
PMCPMC6711515

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.