Evidence map›Paper›PMID 31454369›Full record

ArticlePloS one2019

New diagnostic technique to evaluate hepatic steatosis using the attenuation coefficient on ultrasound B mode.

Yohei Koizumi, Masashi Hirooka, Nobuharu Tamaki, Norihisa Yada, Osamu Nakashima, Namiki Izumi, Masatoshi Kudo, Yoichi Hiasa

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yohei KoizumiDepartments of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.
Masashi HirookaDepartments of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.
Nobuharu TamakiDepartment of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Norihisa YadaDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Kindai University, Osaka, Japan.
Osamu NakashimaPathology Division, Kurume University Hospital, Fukuoka, Japan.
Namiki IzumiDepartment of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Kindai University, Osaka, Japan.
Yoichi HiasaDepartments of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.ORCID 0000-0003-4117-339X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe have developed a diagnostic technique to evaluate hepatic steatosis using the attenuation coefficient (ATT) in ultrasound B mode imaging. A controlled attenuation parameter (CAP) by vibration-controlled transient elastography (VCTE) has also been used to evaluate hepatic steatosis. As that method uses ultrasound A mode, visualizing the liver in real time is difficult. We designed this clinical study to evaluate the diagnostic advantage of our technique using ATT compared to CAP. MATERIALS AND

methodsThe study group included 94 patients with chronic liver disease who had undergone both ATT and CAP assessment at the time of liver biopsy. The M-probe and XL-probe were used for CAP measurement. Data for ATT and CAP were compared as a function of the steatosis grade.

resultsThe area under the receiver operating characteristic curve (AUC-ROCs) for ATT and PAC as a function of the steatosis grade were as follows: grade 1, 0.74 and 0.81; grade 2, 0.80 and 0.85; and grade 3, 0.96 and 0.98, respectively.

conclusionThe accuracy of steatosis grade diagnosis using ATT was the same as that using CAP, with no significant differences and with the added advantage of B mode ultrasound being more convenient and rapid, compared to A mode ultrasound, particularly for patients with subcutaneous fat thickness ≥2 cm.

Indexed as

AlgorithmsUltrasonographyAgedArea Under CurveFatty LiverFemaleHumansMaleROC CurveTime Factors

Identifiers

PMID31454369
PMCPMC6711590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.