Evidence map›Paper›PMID 31454251›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2019

Nanodomain Formation in Planar Supported Lipid Bilayers Composed of Fluid and Polymerized Dienoyl Lipids.

N Malithi Fonseka, Boying Liang, Kristina S Orosz, Ian W Jones, H K Hall, Hamish S Christie, Craig A Aspinwall, S Scott Saavedra

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N Malithi Fonseka
Boying Liang
Kristina S Orosz
Ian W Jones
H K Hall
Hamish S ChristieORCID 0000-0002-8108-6058
Craig A AspinwallORCID 0000-0002-4359-5812

Funding

Sniffer Biosensors Based on Ion Channel-GPCR Chimeras and Polylipid MembranesR01EB007047 · NIBIB · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A, SAAVEDRA, STEVEN SCOTT · 2006 to 2015
$3.5M
Stabilized Biomimetic Separation MediaR01GM095763 · NIGMS · UNIVERSITY OF ARIZONA · PI ASPINWALL, CRAIG A · 2011 to 2014
$1.1M
NIBIB NIH HHS R01 EB007047NIGMS NIH HHS R01 GM095763
6 · The paper itself

Abstract

Polymerization of synthetic phospholipid monomers has been widely used to enhance the stability of lipid membranes in applications such as membrane-based biosensing, where the inherent instability of fluid-phase lipid bilayers can be problematic. However, lipid polymerization typically decreases membrane fluidity, which may be required to maintain the activity of reconstituted integral proteins and peptides. Prior work has shown that a bilayer composed of binary mixtures of poly(lipid) and fluid lipid exhibits enhanced stability and supports the function of incorporated biomolecules. This work examines the structural basis of these findings using planar supported lipid bilayers (PSLBs) composed of binary mixtures of a polymerizable lipid, 1,2-bis[10-(2',4'-hexadienoloxy)decanoyl]-

Indexed as

NanotechnologyPolymerizationDiffusionLipid BilayersPhospholipidsLipid BilayersPhospholipids

Identifiers

PMID31454251
PMCPMC7719349

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.