Evidence map›Paper›PMID 31454105›Full record

ArticleJournal of veterinary internal medicine2019

Mycoplasma haemolamae and intestinal parasite relationships with erythrocyte variables in clinically healthy alpacas and llamas.

Lisa C Viesselmann, Ricardo Videla, John Schaefer, Aly Chapman, Heidi Wyrosdick, Deanna M W Schaefer

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Challenges in Veterinary Vaccine Development.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lisa C ViesselmannDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee.ORCID https://orcid.org/0000-0002-3122-263X
Ricardo VidelaDepartment of Large Animal Clinical Sciences, University of Tennessee, Knoxville, Tennessee.
John SchaeferDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee.
Aly ChapmanDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee.
Heidi WyrosdickDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee.
Deanna M W SchaeferDepartment of Biomedical and Diagnostic Sciences, University of Tennessee, Knoxville, Tennessee.
Knoxville College · USUniversity of Tennessee at Knoxville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycoplasma haemolamae (Mhl) and gastrointestinal nematodes can cause anemia in camelids. Control programs aim to suppress parasitism without promoting anthelminthic resistance, but few evidence-based guidelines define acceptable parasite loads in camelids. HYPOTHESIS/

objectivesIn clinically healthy nonanemic camelids, compare erythrocyte variables to Mhl real-time PCR status and to fecal egg count (FEC). Determine the FEC threshold above which erythrocyte variables are consistently below reference interval medians. ANIMALS: One hundred fourteen client-owned adult alpacas and llamas.

methodsIn a cross-sectional study, whole blood in ethylenediaminetetraacetic acid (EDTA) was assessed for packed cell volume (PCV) by centrifugation, erythrocyte count (RBC), and hemoglobin concentration (HGB) using an ADVIA120 analyzer, and Mhl using real-time PCR. Trichostrongyle eggs per gram (epg) were counted by modified McMaster test on freshly collected feces. Significant differences in erythrocyte variables based on Mhl status and FEC thresholds were assessed by independent t test and one-way ANOVA, respectively.

resultsPacked cell volume, RBC, and HGB were not significantly different between Mhl-positive and Mhl-negative animals, but were significantly lower in animals with FEC >1000 epg compared to those with <500 epg. All animals with FEC >600 epg had RBC and HGB below the reference interval median. All animals with FEC >750 epg had PCV below the reference interval median. CONCLUSIONS AND CLINICAL IMPORTANCE: In healthy nonanemic camelids, positive Mhl PCR is not associated with lower erythrocyte variables and such animals may not warrant treatment. Fecal egg count >600-750 epg has a negative effect on erythrocyte variables, and may be a guide for deworming protocols.

Indexed as

AnimalsCamelids, New WorldCross-Sectional StudiesErythrocyte CountFemaleHematocritHemoglobinsMaleMycoplasmaMycoplasma InfectionsParasite Egg CountReal-Time Polymerase Chain ReactionTennesseeTrichostrongyloideaTrichostrongyloidiasisHemoglobinsanemiacamelidendoparasitefecal egg counthemoparasite

Identifiers

PMID31454105
PMCPMC6766537
OpenAlexW2970739841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.