ReviewActa paediatrica (Oslo, Norway : 1992)2020
Updated Italian recommendations for the diagnosis, treatment and follow-up of the first febrile urinary tract infection in young children.
Review in Acta paediatrica (Oslo, Norway : 1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06164600 (Bovine Colostrum Supplementation for Prophylaxis Against Recurrent Urinary Tract Infection in Children), which is not on this map. Cited by 69 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bovine Colostrum Supplementation for Prophylaxis Against Recurrent Urinary Tract Infection in Children
Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Summary of best evidence on health education for pediatric urinary tract infections.Frontiers in public health · 2026Pooled it
- Kidney and urogenital abnormalities in Down syndrome: a meta-analysis.Italian journal of pediatrics · 2024Pooled it
- A Systematic Review of the (Un)known Host Immune Response Biomarkers for Predicting Recurrence of Urinary Tract Infection.Frontiers in medicine · 2022Pooled it
- Oral steroids for reducing kidney scarring in young children with febrile urinary tract infections: the contribution of Bayesian analysis to a randomized trial not reaching its intended sample size.Pediatric nephrology (Berlin, Germany) · 2021Trial
- Trial
- Tailoring discharge planning after pediatric febrile urinary tract infection: a cohort study.European journal of pediatrics · 2026Article
- Diagnostic yield of urinary tract ultrasound in children following a first urinary tract infection: a retrospective cohort study.Pediatric radiology · 2026Article
- Is uromodulin a reliable biomarker in pediatric vesicoureteral reflux? An exploratory pilot study.International urology and nephrology · 2026Article
- Antibiotic Stewardship in Pediatric Urinary Tract Infections: Current Evidence and Practical Strategies.Antibiotics (Basel, Switzerland) · 2026Review
- Voiding cystourethrography for the pediatric nephrologist: clinical value, challenges, and areas of debate.Pediatric nephrology (Berlin, Germany) · 2026Review
- Persistent use of broad-spectrum antibiotics for suspected community acquired urinary tract infections in children in Italian primary care settings.Italian journal of pediatrics · 2026Article
- The Invisible Excess: Too Long Antibiotic Duration in the Pediatric Emergency Care.Antibiotics (Basel, Switzerland) · 2026Article
- Congenital urinary tract dilation: when is it clinically significant and when should it prompt intervention?Frontiers in pediatrics · 2026Article
- Predictors of recurrence and renal scarring post-urinary tract infection among young febrile infants.BMC pediatrics · 2025Article
- Usefulness of Enhanced Urine Analysis in Febrile Urinary Tract Infection.Journal of pharmacy & bioallied sciences · 2025Article
- Kidney involvement during the course of febrile urinary tract infection.Pediatric nephrology (Berlin, Germany) · 2025Review
- Controversies in treating febrile infantile urinary tract infection caused by extended-spectrum beta-lactamase producing Enterobacteriaceae: an international multi-centre survey.Pediatric nephrology (Berlin, Germany) · 2025Article
- Prediction model for severe vesicoureteral reflux in children with urinary tract infection and/or hydronephrosis.Pediatric nephrology (Berlin, Germany) · 2025Article
- Adherence to the Swedish paediatric guidelines for urinary tract infections.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Kidney Transplantation in Congenital Abnormalities of Kidney and Urinary Tract (CAKUT).Biomedicines · 2025Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimOur aim was to update the recommendations for the diagnosis, treatment and follow-up of the first febrile urinary tract infection in young children, which were endorsed in 2012 by the Italian Society of Pediatric Nephrology.
methodsThe Italian recommendations were revised on the basis of a review of the literature published from 2012 to October 2018. We also carried out an ad hoc evaluation of the risk factors to identify children with high-grade vesicoureteral reflux or renal scarring, which were published in the previous recommendations. When evidence was not available, the working group held extensive discussions, during various meetings and through email exchanges.
resultsFour major modifications have been introduced. The method for collecting urine for culture and its interpretation has been re-evaluated. We have reformulated the algorithm that guides clinical decisions to proceed with voiding cystourethrography. The suggested antibiotics have been revised, and we have recommended further restrictions of the use of antibiotic prophylaxis.
conclusionThese updated recommendations have now been endorsed by the Italian Society of Pediatric Nephrology and the Italian Society for Pediatric Infectivology. They can also be used to compare other recommendations that are available, as a worldwide consensus in this area is still lacking.
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