ArticleMenopause (New York, N.Y.)2019
Age at natural menopause and physical functioning in postmenopausal women: the Canadian Longitudinal Study on Aging.
Article in Menopause (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed.
- Vitamin D3 supplementation enhances the effect of aerobic water-based training on physical fitness indices in obese and overweight menopausal women: A randomized controlled trial.Women's health (London, England)Trial
- Incidence and factors associated with premature ovarian insufficiency: a population-based cohort study.Human reproduction (Oxford, England) · 2026Article
- Age at menopause,Research square · 2026Article
- Impact of timing of menopause on musculoskeletal disorders and associated pain in community-dwelling women: the Yakumo study.International orthopaedics · 2026Article
- Incidence of Metabolic Dysfunction-Associated Steatotic Liver Disease After Developing Depression: A Population-Based Cohort Study.Journal of Korean medical science · 2026Article
- Obstetric and urogynecological history are associated with lower limb strength and physical performance in middle-age and older women: a community-based cross-sectional study.BMC women's health · 2026Observational
- Menopause and its effects on autonomic regulation of blood pressure: Insights and perspectives.Autonomic neuroscience : basic & clinical · 2025Review
- Associations between oxidation balance score and abdominal aortic calcification, and the mediating role of glycohemoglobin: a nationally representative cross-sectional study from NHANES.Frontiers in nutrition · 2025Article
- Type of menopause, age of menopause and cardiovascular disease: a cross-sectional study based on data from Rafsanjan cohort study.BMC women's health · 2024Article
- Gender-related differences in left atrial strain mechanics and exercise capacity in hypertrophic cardiomyopathy: a propensity-score matched study from the Cleveland Clinic.Cardiovascular diagnosis and therapy · 2024Article
- Association of Hormonal Exposures With Grip Strength in Women >45 Years: Data From the CONSTANCES Cohort Study.Journal of the Endocrine Society · 2024Article
- Low physical function following cancer diagnosis is associated with higher mortality risk in postmenopausal women.Journal of the National Cancer Institute · 2024Article
- Reproductive factors and risk of physical frailty among Chinese women living in Singapore.The journal of nutrition, health & aging · 2024Article
- The contributions of fertility during adolescence to disability across the life-course: hypothesized causal pathways, research gaps, and future directions.Annals of human biology · 2024Review
- Estimation of Sarcopenia Indices in Women from Saudi Arabia in Relation to Menopause and Obesity: Cross-Sectional Comparative Study.Journal of clinical medicine · 2023Article
- Unraveling female reproductive senescence to enhance healthy longevity.Cell research · 2023Review
- Changes in women's physical function in mid-life by reproductive age and hormones: a longitudinal study.BMC women's health · 2022Article
- Association between Menopausal Hormone Therapy and Frailty: Cross-Sectional Study Using National Survey Data in Korea.Healthcare (Basel, Switzerland) · 2022Article
- Associations of Age at Menopause With Postmenopausal Bone Mineral Density and Fracture Risk in Women.The Journal of clinical endocrinology and metabolism · 2022Article
- Cost-effectiveness Analysis of Genotype-Specific Surveillance and Preventive Strategies for Gynecologic Cancers Among Women With Lynch Syndrome.JAMA network open · 2021Article
Corrections and comments
- Commented on by
- Commented on byTo the Editor.2020
- Commented on byIn Reply.2020
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
objectiveThe aim of this study was to evaluate the association between categories of age at natural menopause (ANM) and gait speed (slowness) and grip strength (weakness), common measures of physical functioning in older women.
methodsWe analyzed data from the Canadian Longitudinal Study on Aging, which included participants from seven cities across Canada collected in 2012. The sample was restricted to women who reported to have entered menopause (N = 9,920). Women who had a hysterectomy before menopause were excluded since the age at which this surgical procedure was performed was not available. ANM was categorized into five groups: less than 40 (premature), 40 to 44 (early), 45 to 49, 50 to 54, and more than 54. We conducted linear regressions to assess the association between ANM and gait speed (m/s) and grip strength (kg) adjusting for participant age, education, body mass index, smoking, use of hormone therapy, height, and province of residence.
resultsMean ANM was 49.8 (95% confidence interval [CI]: 49.7-50.0), with 3.8% of women having a premature menopause; the average gait speed was 0.98 m/s (standard deviation: 0.22), the average grip strength was 26.6 kg (standard deviation: 6.39). Compared to women with ANM of 50 to 54, women with premature menopause had 0.054 m/s (95% CI -0.083, -0.026) lower gait speed when adjusting for age and study site. In the fully adjusted model, the association was attenuated, 0.032 m/s (95% CI -0.060, -0.004). ANM was not associated with grip strength.
conclusionOur study suggests that premature menopause (<40 years) may be associated with lower gait speed (slowness) among Canadian women. No association was observed between ANM and grip strength. Future studies should include a life course approach to evaluate whether social and biological pathways modify the association between age at menopause and physical function in populations from different contexts.
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