Evidence map›Paper›PMID 31453766›Full record

ArticleRadiology2019

Left Ventricular Mass at MRI and Long-term Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis (MESA).

Nadine Kawel-Boehm, Richard Kronmal, John Eng, Aaron Folsom, Gregory Burke, J Jeffrey Carr, Steven Shea, João A C Lima, David A Bluemke

Registry-linked trialOpen access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07270367 (Finerenone and Cardiac Remodeling), which is not on this map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07270367 phase3not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Finerenone and Cardiac Remodeling: A Randomized, Double- Blind, Placebo-Controlled Study to Evaluate The Effects of Finerenone on Ventricular Remodeling

TypeinterventionalSponsorSubodh VermaRan2025 to 2030Enrolled156ConditionsHeart FailureArmsFinerenone, Placebo
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 93 citations in OpenAlex.

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  14. Deciphering epistatic genetic regulation of cardiac hypertrophy.medRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Nadine Kawel-BoehmFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).ORCID 0000-0001-5594-8892
Richard KronmalFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).
John EngFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).ORCID 0000-0002-9129-5160
Aaron FolsomFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).
Gregory BurkeFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).
J Jeffrey CarrFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).ORCID 0000-0002-4398-8237
Steven SheaFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).
João A C LimaFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).ORCID 0000-0001-8756-6995
David A BluemkeFrom the Department of Radiology, Kantonsspital Graubuenden, Loestrasse 170, 7000 Chur, Switzerland (N.K.); Collaborative Health Studies Coordinating Center, University of Washington, Seattle, Wash (R.K.); Department of Radiology and Radiological Science (J.E.) and Division of Cardiology (J.A.C.L.), Johns Hopkins University, Baltimore, Md; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minn (A.F.); Department of Public Health Sciences, Wake Forest University, Winston-Salem, NC (G.B.); Department of Radiology, Vanderbilt University Medical Center, Nashville, Tenn (J.J.C.); Department of Medicine, Columbia University, New York, NY (S.S.); and Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wis (D.A.B.).ORCID 0000-0002-8323-8086
Johns Hopkins University · USUniversity of Minnesota · USUniversity of Wisconsin–Madison · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Cigarette Smoke and Susceptibility to Influenza InfectionR01HL095163 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, NOAH, TERRY L · 2009 to 2013
$2.0M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095161 · HC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN · 1999 to 2001
$642k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1999 to 2001
$616k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095160 · HC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SAAD, MOHAMMED F · 1999 to 2001
$592k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095164 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1999 to 2001
$511k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095163 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI FOLSOM, AARON R · 1999 to 2001
$443k
Enhancing immune reconstitution after implantation of postnatal allogeneic thymusR21HL095165 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CROOKS, GAY M · 2008 to 2009
$440k
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169
6 · The paper itself

Abstract

Background Few data exist on the long-term risk prediction of elevated left ventricular (LV) mass quantified by MRI for cardiovascular (CV) events in a contemporary, ethnically diverse cohort. Purpose To assess the long-term impact of elevated LV mass on CV events in a prospective cohort study of a multiethnic population in relationship to risk factors and coronary artery calcium (CAC) score. Materials and Methods The Multi-Ethnic Study of Atherosclerosis, or MESA (

Indexed as

EthnicityAgedAged, 80 and overAtherosclerosisCohort StudiesComorbidityFemaleHeart FailureHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance ImagingMaleMiddle AgedMyocardial InfarctionProspective Studies

Identifiers

PMID31453766
PMCPMC6776886
OpenAlexW2970272920

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.