Evidence map›Paper›PMID 31453649›Full record

ArticleGlia2020

Monocarboxylate transporter 1 in Schwann cells contributes to maintenance of sensory nerve myelination during aging.

Mithilesh Kumar Jha, Youngjin Lee, Katelyn A Russell, Fang Yang, Raha M Dastgheyb, Pragney Deme, Xanthe H Ament, Weiran Chen, Ying Liu, Yun Guan and 5 more

Open access · greenAbstract read
In one paragraph

Article in Glia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 68 citations in OpenAlex.

  1. Dyslipidemia is a metabolic hallmark of acute pain in sickle cell disease.medRxiv : the preprint server for health sciences · 2026
    Article
  2. Intrathecal (GActa neuropathologica communications · 2026
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  3. Stem cell functionbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Intrathecal (GbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Lactate promotes longevity through redox-driven lipid remodeling inbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. [Research advances on the role of Schwann cells in diabetic peripheral neuropathy].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 2 countries.

Mithilesh Kumar JhaDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-9526-0053
Youngjin LeeDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Katelyn A RussellDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Fang YangDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Raha M DastgheybDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Pragney DemeDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Xanthe H AmentDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Weiran ChenDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ying LiuDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Yun GuanDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Michael J PolydefkisDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ahmet HokeDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Norman J HaugheyDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0001-5194-4122
Jeffrey D RothsteinDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-2001-8470
Brett M MorrisonDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0001-5404-3899
Johns Hopkins University · US

Funding

Role of Monocarboxylate Transporters in the Recovery from Peripheral Nerve InjuryR01NS086818 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MORRISON, BRETT M. · 2015 to 2019
$1.8M
NIH HHS NS086818-01NINDS NIH HHS R01 NS086818
6 · The paper itself

Abstract

Schwann cell (SC)-specific monocarboxylate transporter 1 (MCT1) knockout mice were generated by mating MCT1

Indexed as

AgingAnimalsCells, CulturedFemaleMaleMiceMice, KnockoutMice, TransgenicMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersMyelin SheathNeural ConductionSchwann CellsSensory Receptor CellsSural NerveSymportersMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymporterslactateMCT1metabolismmonocarboxylate transportermyelinationperipheral nerveSchwann cellsensory axonstriacylglycerides

Identifiers

PMID31453649
PMCPMC7054847
OpenAlexW2970711514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.