Evidence map›Paper›PMID 31453298›Full record

ArticleData in brief2019

Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome.

Carolina Balbi, Kirsten Lodder, Ambra Costa, Silvia Moimas, Francesco Moccia, Tessa van Herwaarden, Vittorio Rosti, Francesca Campagnoli, Agnese Palmeri, Pierangela De Biasio and 6 more

Abstract read
In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
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  5. Article
  6. Review
  7. Review
  8. Article
  9. The human amniotic fluid stem cell secretome triggers intracellular CaJournal of cellular and molecular medicine · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Carolina BalbiRegenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy.
Kirsten LodderDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Ambra CostaRegenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy.
Silvia MoimasMolecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Francesco MocciaGeneral Physiology Laboratory, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
Tessa van HerwaardenDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Vittorio RostiLaboratory of Biochemistry, Biotechnology and Advanced Diagnostic, Myelofibrosis Study Centre, IRCCS Ospedale Policlinico San Matteo, Pavia, Italy.
Francesca CampagnoliRegenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy.
Agnese PalmeriDept. of Obstetrics and Gynecology, Ospedale Policlinico San Martino - IRCCS per l'Oncologia, Genova, Italy.
Pierangela De BiasioDept. of Obstetrics and Gynecology, Ospedale Policlinico San Martino - IRCCS per l'Oncologia, Genova, Italy.
Francesco SantiniDivision of Cardiac Surgery, Ospedale Policlinico San Martino - IRCCS per l'Oncologia, Genova, Italy.
Mauro GiaccaMolecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Marie-Josè GoumansDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Lucio BarileMolecular and Cell Cardiology Laboratory, CardioCentro Ticino, Lugano, Switzerland.
Anke M SmitsDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
Sveva BolliniRegenerative Medicine Laboratory, Department of Experimental Medicine, University of Genova, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The data and information presented here refer to the research article entitled: "Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting with the human amniotic fluid stem cell secretome" (Balbi et al., 2019, Apr 04). This dataset illustrates the in vitro paracrine effect exerted by the human amniotic fluid stem cell secretome on rodent neonatal cardiomyocytes, human endothelial progenitors and different subsets of cardiac progenitor cells. Cytokine/chemokine profiling of the human amniotic fluid stem cell secretome is provided as well. This data can provide useful insights in regenerative medicine as demonstrating the in vitro cardioprotective and proliferative secretory paracrine potential of human fetal stem cells.

Indexed as

AngiogenesisCardiac progenitor cellsCardioprotectionEndothelial progenitorsHuman amniotic fluid stem cellsNeonatal cardiomyocytesParacrine effectProliferation

Identifiers

PMID31453298
PMCPMC6700494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.