Evidence map›Paper›PMID 31453251›Full record

ArticleJournal of biological methods2018

An automated quantitative image analysis pipeline of

Andre D Paredes, David Benavidez, Jun Cheng, Steve Mangos, Michael Donoghue, Amelia Bartholomew

Abstract read
In one paragraph

Article in Journal of biological methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andre D ParedesRichard and Loan Hill Department of Bioengineering, University of Illinois, Chicago, IL 60612, USA.
David BenavidezDepartment of Surgery, University of Illinois, Chicago, IL 60612, USA.
Jun ChengRichard and Loan Hill Department of Bioengineering, University of Illinois, Chicago, IL 60612, USA.
Steve MangosDepartment of Internal Medicine, Rush University, Chicago, IL 60612, USA.
Michael DonoghueDonoghue Chiropractic, Lincolnshire, IL 60069, USA.
Amelia BartholomewRichard and Loan Hill Department of Bioengineering, University of Illinois, Chicago, IL 60612, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophage behavior is of great interest in response to tissue injury and promotion of regeneration. With increasing numbers of zebrafish reporter-based assays, new capabilities now exist to characterize macrophage migration, and their responses to biochemical cues, such as reactive oxygen species. Real time detection of macrophage behavior in response to oxidative stress using quantitative measures is currently beyond the scope of commercially available software solutions, presenting a gap in understanding macrophage behavior. To address this gap, we developed an image analysis pipeline solution to provide real time quantitative measures of cellular kinetics and reactive oxygen species content

Indexed as

cell kineticsoxidative stressquantitative image analysistime-lapse imagingzebrafish

Identifiers

PMID31453251
PMCPMC6706154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.