Evidence map›Paper›PMID 31453247›Full record

ArticleJournal of biological methods2018

A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells.

Matthew S Alexander, Brianne R O'Leary, Devon Moose, Juan Du, Michael D Henry, Joseph J Cullen

Open access · diamondAbstract read
In one paragraph

Article in Journal of biological methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Matthew S AlexanderDepartments of Surgery, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Brianne R O'LearyDepartments of Surgery, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Devon MooseDepartments of Molecular Physiology and Biophysics, Pathology and Urology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Juan DuDepartments of Surgery, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Michael D HenryDepartments of Molecular Physiology and Biophysics, Pathology and Urology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
Joseph J CullenDepartments of Surgery, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
University of Iowa · USUniversity of Iowa Holden Comprehensive Cancer CenterUniversity of Iowa Hospitals and Clinics · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
Project 3: MRI Imaging of Redox Active Fe Predicts GBM Responses to Pharmacological AscorbateP01CA217797 · NCI · UNIVERSITY OF IOWA · PI BUATTI, JOHN M · 2018 to 2022
$9.6M
University of Iowa Surgical Oncology Training GrantT32CA148062 · NCI · UNIVERSITY OF IOWA · PI WEIGEL, RONALD J · 2010 to 2020
$3.8M
Predoctoral Training in the Pharmacological SciencesT32GM067795 · NIGMS · UNIVERSITY OF IOWA · PI STRACK, STEFAN · 2004 to 2021
$3.4M
Pharmacological Ascorbate as a Radiosensitizer in Pancreatic CancerR01CA184051 · NCI · UNIVERSITY OF IOWA · PI CULLEN, JOSEPH J · 2015 to 2018
$1.4M
BLRD VA I01 BX001318NCI NIH HHS P01 CA217797NCI NIH HHS P30 CA086862NCI NIH HHS R01 CA184051NCI NIH HHS T32 CA148062NIGMS NIH HHS T32 GM067795
6 · The paper itself

Abstract

Metastatic disease is the leading cause of pancreatic ductal adenocarcinoma (PDAC) associated death. PDAC cells invade and enter the bloodstream early, before frank malignancy can be detected. Our objective was to develop an

Indexed as

bioluminescent imagingcirculating tumor cellsmetastasisorthotopic implantationpancreatic adenocarcinoma

Identifiers

PMID31453247
PMCPMC6706145
OpenAlexW2890172277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.