Evidence map›Paper›PMID 31453199›Full record

ArticleJournal of advanced veterinary and animal research2019

Antibacterial efficacy of ethanolic extract of

Md Asief Hossain Zihadi, Marzia Rahman, Sudipta Talukder, Md Mehedi Hasan, Samsun Nahar, Mahmudul Hasan Sikder

Abstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Prevention and Treatment ofPathogens (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Expanded Therapeutic Applications ofCombinatorial chemistry & high throughput screening · 2024
    Review
  4. Article
  5. Baicalein Inhibits theInfection and drug resistance · 2023
    Article
  6. Article
  7. The Antimicrobial Potential of the Neem TreeFrontiers in pharmacology · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Md Asief Hossain ZihadiDepartment of Pharmacology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Marzia RahmanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Sudipta TalukderDepartment of Medicine, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Md Mehedi HasanDepartment of Medicine, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Samsun NaharDepartment of Physiology, Holy Family Red Crescent Medical College, Dhaka, Bangladesh.
Mahmudul Hasan SikderDepartment of Pharmacology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims at investigating the antibacterial potential of ethanolic extract of MATERIALS AND

methodsFresh leaves were processed and extracted by 99% ethanol and reconstituted with 50% ethanol before testing. Disk diffusion and broth microdilution methods were used to determine zone diameter of inhibition (ZDI) and minimum inhibitory concentration (MIC), respectively. Nutrient agar plate was used to estimate the minimum bactericidal concentration (MBC).

resultsMaximum ZDI value was observed for green tea against MRSA (7.5 mm) and minimum for neem (4.9 mm). Moreover, the highest ZDI against STEC was also for green tea and the combination of green tea and neem (4.5 mm). The MIC values of green tea extract were 15.625 and 31.25 mg/ml against MRSA and STEC, respectively, whereas the MIC of neem was 31.25 and 125 mg/ml, respectively. The combination had similar MIC (46.87 mg/ml) against both organisms. Green tea showed the lowest MBC values, 31.25 and 62.5 mg/ml, against MRSA and STEC, respectively. However, MBC of neem and the combination against MRSA and STEC were found >250 mg/ml, >500 mg/ml and 93.75 mg/ml, >375 mg/ml, respectively.

conclusionGreen tea and neem leaves showed good antimicrobial effects and can be used to explore novel antimicrobial compounds against MRSA and STEC.

Indexed as

green teaMICMRSAmulti-drug resistantneemSTEC

Identifiers

PMID31453199
PMCPMC6702883

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.