Evidence map›Paper›PMID 31453046›Full record

ArticleCurrent addiction reports2019

A Review of the Use and Appeal of Flavored Electronic Cigarettes.

Nicholas I Goldenson, Adam M Leventhal, Kelsey A Simpson, Jessica L Barrington-Trimis

Registry-linked trialAbstract read
In one paragraph

Article in Current addiction reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06506162 (The Effect of Flavor and Nicotine Strength on the Abuse Liability and Appeal of Oral Nicotine Products), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06506162 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Flavor and Nicotine Strength on the Abuse Liability and Appeal of Oral Nicotine Products

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2024 to 2028Enrolled320ConditionsNicotine DependenceArmsFlavor, Nicotine concentration
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Appeal and Sensory Characteristics of Oral Nicotine Products in Young Adults Who Vape E-Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Trial
  6. Trial
  7. Effect on Tobacco Use and Subjective Measures of Including E-cigarettes in a Simulated Ban of Menthol in Combustible Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
  8. Article
  9. Review
  10. Article
  11. Racial and/or Ethnic, Sex, and Age Differences in Smoking Prevalences Among Youth and Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas I GoldensonDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA.
Adam M LeventhalDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA.
Kelsey A SimpsonDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA.
Jessica L Barrington-TrimisDepartment of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA.

Funding

USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jessica Louise Barrington-Trimis · 2018 to 2026
$39.0M
USC Tobacco Center of Regulatory Science (TCORS) for Vulnerable PopulationsP50CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PENTZ, MARY ANN, SAMET, JONATHAN M · 2013 to 2017
$20.1M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
Understanding Transitions from Vaping to Smoking Across AdolescenceK01DA042950 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE · 2017 to 2021
$1.0M
NCI NIH HHS P50 CA180905NCI NIH HHS U54 CA180905NIDA NIH HHS K01 DA042950NIDA NIH HHS K24 DA048160
6 · The paper itself

Abstract

purpose of reviewE-cigarettes are available in a variety of flavors not found in traditional tobacco products (i.e., "nontraditional flavors"), which is a commonly-cited reason for e-cigarette use. This review examines the prevalence of nontraditional-flavored e-cigarette use, mechanisms through which flavorings enhance product appeal, use of nontraditional-flavored e-cigarettes for smoking cessation, and differences in these findings between youth and adults. RECENT

findingsNontraditional-flavored e-cigarettes are used at e-cigarette initiation by the majority of youth. These flavors enhance the appeal of e-cigarettes by creating sensory perceptions of sweetness and coolness and masking the aversive taste of nicotine. Use of nontraditional-flavored e-cigarettes is higher among youth and young adults (vs. older adults) and among nonsmokers (vs. combustible cigarette smokers). SUMMARY: Nontraditional-flavored e-cigarettes are popular among youth, but may be less common among older adults and combustible cigarette smokers. Further research is needed to determine whether use of e-cigarettes in nontraditional flavors affects smoking cessation.

Indexed as

appealelectronic cigaretteflavorflavoredvaping

Identifiers

PMID31453046
PMCPMC6709993

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.