Evidence map›Paper›PMID 31453017›Full record

ArticleGlobal advances in health and medicine2019

Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial.

E Anne Lown, Anu Banerjee, Eric Vittinghoff, Christopher C Dvorak, Wendy Hartogensis, Alexis Melton, Christina Mangurian, Hiroe Hu, Deborah Shear, Robyn Adcock and 3 more

Open access · goldAbstract read
In one paragraph

Article in Global advances in health and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

E Anne LownSocial and Behavioral Sciences, School of Nursing, University of California, San Francisco, California.ORCID https://orcid.org/0000-0002-7502-4459
Anu BanerjeeDepartment of Neurological Surgery, University of California, San Francisco, California.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, California.ORCID https://orcid.org/0000-0001-8535-0920
Christopher C DvorakDivision of Pediatric Allergy, Immunology, & Blood and Marrow Transplantation, University of California, San Francisco, California.
Wendy HartogensisOsher Center for Integrative Medicine, University of California, San Francisco, California.
Alexis MeltonDivision of Pediatric Allergy, Immunology, & Blood and Marrow Transplantation, University of California, San Francisco, California.
Christina MangurianDepartment of Psychiatry, School of Medicine, University of California, San Francisco, California.
Hiroe HuSocial and Behavioral Sciences, School of Nursing, University of California, San Francisco, California.
Deborah ShearSocial and Behavioral Sciences, School of Nursing, University of California, San Francisco, California.
Robyn AdcockCompass Care/Integrative Pediatric Pain and Palliative Care (IP3), UCSF Benioff Children's Hospital, San Francisco, California.
Michael MorganSocial and Behavioral Sciences, School of Nursing, University of California, San Francisco, California.
Carla GoldenDepartment of Pediatric Hematology-Oncology, UCSF Benioff Children's Hospital, Oakland, California.
Frederick M HechtOsher Center for Integrative Medicine, University of California, San Francisco, California.
University of California, San Francisco · USUCSF Benioff Children's Hospital · US

Funding

Mentoring and Research in Integrative MedicineK24AT007827 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2013 to 2022
$1.8M
NCCIH NIH HHS K24 AT007827
6 · The paper itself

Abstract

backgroundWe describe the study design and protocol of a pragmatic randomized controlled trial (RCT) Acupressure for Children in Treatment for a Childhood Cancer (ACT-CC).

objectiveTo describe the feasibility and effectiveness of an acupressure intervention to decrease treatment-related symptoms in children in treatment for cancer or recipients of a chemotherapy-based hematopoietic stem cell transplant (HSCT).

designTwo-armed RCTs with enrollment of 5 to 30 study days.

settingTwo pediatric teaching hospitals. PATIENTS: Eighty-five children receiving cancer treatment or a chemotherapy-based HSCT each with 1 parent or caregiver.

interventionPatients are randomized 1:1 to receive either usual care plus daily professional acupressure and caregiver delivered acupressure versus usual care alone for symptom management. Participants receive up to 20 professional treatments. MAIN OUTCOME: A composite nausea/vomiting measure for the child. SECONDARY OUTCOMES: Child's nausea, vomiting, pain, fatigue, depression, anxiety, and positive affect. PARENT OUTCOMES: Depression, anxiety, posttraumatic stress symptoms, caregiver self-efficacy, and positive affect. Feasibility of delivering the semistandardized intervention will be described. Linear mixed models will be used to compare outcomes between arms in children and parents, allowing for variability in diagnosis, treatment, and age. DISCUSSION: Trial results could help childhood cancer and HSCT treatment centers decide about the regular inclusion of trained acupressure providers to support symptom management.

Indexed as

acupressureacupuncturechildhood cancernauseapainsymptom managementvomiting

Identifiers

PMID31453017
PMCPMC6696841
OpenAlexW2968691576

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.