Evidence map›Paper›PMID 31452991›Full record

ArticleBiomedical optics express2019

Pilot study of transcranial photobiomodulation of lymphatic clearance of beta-amyloid from the mouse brain: breakthrough strategies for non-pharmacologic therapy of Alzheimer's disease.

Ekaterina Zinchenko, Nikita Navolokin, Alexander Shirokov, Boris Khlebtsov, Alexander Dubrovsky, Elena Saranceva, Arkady Abdurashitov, Alexander Khorovodov, Andrey Terskov, Aysel Mamedova and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
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  20. Photobiomodulation for Neurodegenerative Diseases: A Scoping Review.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ekaterina ZinchenkoSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Nikita NavolokinSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Alexander ShirokovSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Boris KhlebtsovInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Entusiastov Str. 13, Saratov 410049, Russia.
Alexander DubrovskySaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Elena SarancevaSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Arkady AbdurashitovSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Alexander KhorovodovSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Andrey TerskovSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Aysel MamedovaSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Maria KlimovaSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Ilana AgranovichSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Dmitry MartinovSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Valery TuchinSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Oxana Semyachkina-GlushkovskayaSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.
Jurgen KurtsSaratov State University, Astrakhanskaya Str. 83, Saratov 410012, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this pilot study, we analyzed effects of transcranial photobiomodulation (tPBM, 1267 nm, 32 J/cm

Identifiers

PMID31452991
PMCPMC6701516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.