Evidence map›Paper›PMID 31452975›Full record

ArticleBiomedical optics express2019

Dual-band refractometric terahertz biosensing with intense wave-matter-overlap microfluidic channel.

Feng Lan, Feng Luo, Pinaki Mazumder, Ziqiang Yang, Lin Meng, Zhengqiang Bao, Jun Zhou, Yaxin Zhang, Shixiong Liang, Zongjun Shi and 5 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Feng LanTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Feng LuoTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Pinaki MazumderDepartment of Electrical Engineering and Computer Science, University of Michigan, MI 48109-2121, Ann Arbor, USA.
Ziqiang YangTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Lin MengTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Zhengqiang BaoNanjing Sanle group co.LTD, 211800, Nanjing, China.
Jun ZhouTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Yaxin ZhangTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Shixiong LiangThe 13th Research Institute of China Electronic Science and Technology Group Corporation, 050051, Shijiazhuang, China.
Zongjun ShiTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Abdur Rauf KhanTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Ziqi ZhangTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Luyang WangTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Jing YinTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.
Hongxin ZengTerahertz Research Centre, School of Electronic Science and Engineering University of Electronic Science and Technology of China, 610054, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We theoretically and experimentally demonstrate a label-free terahertz biosensor with ultrahigh sensitivity and distinctive discretion. By constructing a metal-air-metal (MAM) metamaterial perfect absorber (MPA) with a metallic paired-ring resonator array, a hollow microfluidic channel, and a backed reflector, a novel dual-band absorptive sensing platform is proposed in the THz range. The near field coupling by dipole-induced trapped modes and the magnetic momentum caused a vertical to transverse power flux that dramatically enhanced the electromagnetic field on top of the metasurface and in the microfluidic channel, respectively. Both the resonant modes exhibit perfect absorption and produce ultrahigh normalized sensitivities of 0.47/RIU (refractive index unit, RIU) and 0.51/RIU at 0.76 THz and 1.28 THz, respectively. Compared with conventional microfluidic sensors, the salient advantages of our design are the perfect spatial overlap for light-matter interaction and polarization insensitivity. Characterized by THz time domain spectroscopic absorption quantification measurements with different concentrations of bovine serum albumin (BSA), the proposed sensor exhibits promising applications in microfluidic biosensing.

Identifiers

PMID31452975
PMCPMC6701553

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.