ArticleJournal of pharmaceutical analysis2019
Interaction of repaglinide with bovine serum albumin: Spectroscopic and molecular docking approaches.
Article in Journal of pharmaceutical analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 99 citations in OpenAlex.
- Elucidating the mechanism of cefpodoxime-BSA interaction via a combination of multi-spectroscopic methods and molecular docking simulations.Scientific reports · 2026Article
- Molecular Insights into the Temperature-Dependent Binding and Conformational Dynamics of Noraucuparin with Bovine Serum Albumin: A Microsecond-Scale MD Simulation Study.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Molecular interaction study of L-Ornithine with bovine serum albumin using spectroscopic and molecular docking methods.Scientific reports · 2025Article
- Albumin-Based Nanoparticles with Factorial Design as a Promising Approach for Remodeled Repaglinide: Evidence from In Silico, In Vitro, and In Vivo Evaluations.Pharmaceutics · 2025Article
- Article
- Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule.Heliyon · 2023Article
- Insights on the in-vitro binding interaction between donepezil and bovine serum albumin.BMC chemistry · 2023Article
- Pseudouridimycin-A Potent Nucleoside Inhibitor of the RNA Polymerase Beta Prime Subunit ofACS omega · 2023Article
- Characterization of binding by repaglinide and nateglinide with glycated human serum albumin using high-performance affinity microcolumns.Journal of separation science · 2022Article
- Probing the Interactions of Lamotrigine and Phenobarbital with Tau Protein: Experimental and Molecular Modeling Studies.Iranian journal of pharmaceutical research : IJPR · 2022Article
- Exploring the molecular interaction of mebendazole with bovine serum albumin using multi-spectroscopic approaches and molecular docking.Scientific reports · 2022Article
- Mechanistic interaction studies of synthesized ZIF-8 nanoparticles with bovine serum albumin using spectroscopic and molecular docking approaches.Scientific reports · 2022Article
- Clinical Effects of Exercise Rehabilitation Combined with Repaglinide in the Treatment of Diabetes.Disease markers · 2022Article
- In Vitro Investigation of Binding Interactions between Albumin-Gliclazide Model and Typical Hypotensive Drugs.International journal of molecular sciences · 2021Article
- Effect of Tetraphenylborate on Physicochemical Properties of Bovine Serum Albumin.Molecules (Basel, Switzerland) · 2021Article
- Design and Synthesis of Novel Peptides to Protect Ferulic Acid against Ultraviolet Radiation Based on Domain Site IIA of Bovine Serum Albumin.Biomolecules · 2021Article
- Aflatoxin BACS omega · 2021Article
- High-Performance affinity chromatographic studies of repaglinide and nateglinide interactions with normal and glyoxal- or methylglyoxal-modified human albumin serum.Journal of pharmaceutical and biomedical analysis · 2021Article
- How Does Glycation Affect Binding Parameters of the Albumin-Gliclazide System in the Presence of Drugs Commonly Used in Diabetes? In Vitro Spectroscopic Study.Molecules (Basel, Switzerland) · 2021Article
- Difference in the binding mechanism of distinct antimony forms in bovine serum albumin.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Repaglinide (RPG) regulates the amount of glucose by stimulating the pancreas to release insulin in the blood. In view of its biological importance, we have examined the interaction between RPG and a model protein, bovine serum albumin (BSA) employing various spectroscopic, electrochemical and molecular docking methods. Fluorescence spectra of BSA were recorded in the presence and absence of RPG in phosphate buffer of pH 7.4. Fluorescence intensity of BSA was decreased upon the addition of increased concentrations of RPG, indicating the interaction between RPG and BSA. Stern-Volmer quenching analysis results revealed that RPG quenched the intensity of BSA through dynamic quenching mechanism. This was further confirmed from the time-resolved fluorescence measurements. The binding constant as calculated from the spectroscopic and voltammetric results was observed to be in the order of 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.