ReviewComputational and structural biotechnology journal2019
In-silico Design of DNA Oligonucleotides: Challenges and Approaches.
Review in Computational and structural biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- OligoN-Design: A Simple and Versatile Tool to Design Specific Probes and Primers From Large Heterogeneous Datasets.Molecular ecology resources · 2026Article
- Specificity of Primers and Probes for Molecular Diagnosis ofPathogens (Basel, Switzerland) · 2025Article
- In-silico matching of SARS-CoV-2 genes and oligonucleotides using the Simple Oligo Matching Tool.Genes & genomics · 2025Article
- Dsembler - DNA Assembly Designer: A Tool for Facilitating Assembly of Oligomers.Journal of microbiology and biotechnology · 2025Article
- Exploring precision therapeutics: computational design of antisense oligonucleotides targeting AXL gene transcripts in multiple sclerosis treatment management.Frontiers in chemistry · 2025Article
- DNA-based prediction of external ear morphology in the Chinese population: an exploratory study.PeerJ · 2025Article
- Typing ofFrontiers in microbiology · 2025Article
- Nanocarriers: Exploring the Potential of Oligonucleotide Delivery.Current drug delivery · 2025Review
- Exploring the impact of primer length on efficient gene detection via high-throughput sequencing.Nature communications · 2024Article
- Quantitative detection of cassava common mosaic virus for health certification of cassava (Heliyon · 2024Article
- A tool to automatically design multiplex PCR primer pairs for specific targets using diverse templates.Scientific reports · 2023Article
- Evaluation of loci to predict ear morphology using two SNaPshot assays.Forensic science, medicine, and pathology · 2023Article
- Full pathogen characterisation: species identification including the detection of virulence factors and antibiotic resistance genes via multiplex DNA-assays.Scientific reports · 2021Article
- High Throughput Sequencing for the Detection and Characterization of RNA Viruses.Frontiers in microbiology · 2021Review
- Genetic Approaches for the Treatment of Facioscapulohumeral Muscular Dystrophy.Frontiers in pharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA oligonucleotides are essential components of a high number of technologies in molecular biology. The key event of each oligonucleotide-based assay is the specific binding between oligonucleotides and their target DNA. However, single-stranded DNA molecules also tend to bind to unintended targets or themselves. The probability of such unspecific binding increases with the complexity of an assay. Therefore, accurate data management and design workflows are necessary to optimize the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.