ArticleClinical reviews in bone and mineral metabolism2019
Bone Health in the Transgender Population.
Article in Clinical reviews in bone and mineral metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Nutritional Monitoring During Gender-Affirming Hormone Therapy: Body Composition and Metabolic Implications.Nutrients · 2026Review
- Considerations in Care of the Transgender Orthopedic Patient.Current reviews in musculoskeletal medicine · 2025Review
- Endocrine issues in critically ill transgender patients: A narrative review.World journal of critical care medicine · 2025Review
- A Preclinical Investigation of Estrogenic Bone Protection in a Hypertensive Rat Model Under Gender-Affirming Hormone Therapy.Biology · 2025Article
- Gender Reassignment and the Role of the Laboratory in Monitoring Gender-Affirming Hormone Therapy.Journal of clinical medicine · 2024Review
- Sexual Dimorphism in the Musculoskeletal System: Sex Hormones and Beyond.Journal of the Endocrine Society · 2024Review
- The association of gender-affirming hormone therapy duration and body mass index on bone mineral density in gender diverse adults.Journal of clinical & translational endocrinology · 2024Article
- ESCAP statement on the care for children and adolescents with gender dysphoria: an urgent need for safeguarding clinical, scientific, and ethical standards.European child & adolescent psychiatry · 2024Article
- Strength, power and aerobic capacity of transgender athletes: a cross-sectional study.British journal of sports medicine · 2024Article
- No Bones About It: Sex Is Binary.Archives of sexual behavior · 2024Article
- Bone Density in Transgender Youth on Gender-Affirming Hormone Therapy.Journal of the Endocrine Society · 2024Article
- Three cases highlighting possible discrepancies in the interpretation of transgender DXA scores.Clinical case reports · 2024Article
- Approach to the Patient: Hormonal Therapy in Transgender Adults With Complex Medical Histories.The Journal of clinical endocrinology and metabolism · 2024Article
- Bone quality following peripubertal growth in a mouse model of transmasculine gender-affirming hormone therapy.bioRxiv : the preprint server for biology · 2024Article
- The Utility of Preclinical Models in Understanding the Bone Health of Transgender Individuals Undergoing Gender-Affirming Hormone Therapy.Current osteoporosis reports · 2023Review
- Misgendering a transgender woman using FORDISC 3.1: A case study.Forensic science international. Synergy · 2023Article
- Gender-affirming hormone therapy, mental health, and surgical considerations for aging transgender and gender diverse adults.Therapeutic advances in endocrinology and metabolism · 2023Review
- Article
- SIGIS-SIAMS-SIE position statement of gender affirming hormonal treatment in transgender and non-binary people.Journal of endocrinological investigation · 2022Article
- Bone health in transgender people: a narrative review.Therapeutic advances in endocrinology and metabolism · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It is well known that sex steroids, particularly estrogen, play a crucial role in the attainment and maintenance of peak bone density in all people. Transgender (trans) women have been frequently observed to have low bone density prior to initiation of gender-affirming hormone therapy, while trans men generally do not. With pharmacologic estrogen, many studies show improving bone density in trans women. With pharmacologic testosterone, bone density in trans men remains largely unchanged although androgens have indirect effects on bone health via changes in fat and lean mass. Much remains unknown about best practices to optimize bone health, interpret DXA scans and assess fracture risk in trans adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.