Evidence map›Paper›PMID 31452628›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Multiparametric magnetic resonance imaging-guided salvage radiotherapy in prostate cancer.

Felipe Couñago, Ana Aurora Díaz Gavela, Gemma Sancho, Irene Ortiz, Francisco José Marcos, Manuel Recio, Julio Fernández, Raquel Cano, Mar Jiménez, Israel J Thuissard and 6 more

Abstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Tracing prostate cancer - the evolution of PET-CT applications.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Review
  3. Pathological stage, surgical margin and lymphovascular invasion as prognostic factors after salvage radiotherapy for post-prostatectomy relapsed prostate cancer - outcomes and optimization strategies.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Felipe CouñagoDepartment of Radiation Oncology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Ana Aurora Díaz GavelaDepartment of Radiation Oncology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Gemma SanchoDepartment of Radiation Oncology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona 08041, Spain.
Irene OrtizDepartment of Radiation Oncology, Hospital Universitario Son Espases, Palma de Mallorca 07120, Spain.
Francisco José MarcosDepartment of Radiation Oncology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Manuel RecioDepartment of Radiology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Julio FernándezDepartment of Radiology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Raquel CanoDepartment of Radiology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Mar JiménezDepartment of Radiology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Israel J ThuissardDepartment of Research, Universidad Europea, Madrid 28670, Spain.
David Sanz-RosaClinical Department, Faculty of Biomedicine, Universidad Europea, Madrid 28670, Spain.
Juan Castro NováisDepartment of Medical Physics, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Eduardo PardoDepartment of Medical Physics, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Yolanda MolinaDepartment of Medical Physics, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Hugo Pérez GarcíaDepartment of Medical Physics, Hospital Universitario Quirónsalud, Madrid 28223, Spain.
Elia Del CerroDepartment of Radiation Oncology, Hospital Universitario Quirónsalud, Madrid 28223, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyse the efficacy and toxicity of postprostatectomy SRT in patients with a BCR evaluated with mpMRI.

backgroundMultiparametric magnetic resonance imaging (mpMRI) has the ability to detect the site of pelvic recurrence in patients with biochemical recurrence (BCR) after radical prostatectomy (RP). However, we do not know the oncological outcomes of mpMRI-guided savage radiotherapy (SRT).

resultsLocal, lymph node, and pelvic bone recurrence was observed in 13, 4 and 2 patients, respectively. PSA levels were significantly lower in patients with negative mpMRI (0.4 ng/mL [0.4]) vs. positive mpMRI (2.2 ng/mL [4.1],

conclusionSRT to the macroscopic recurrence identified by mpMRI is a feasible and well-tolerated option. In this study, there were no differences in bRFS between MRI-positive and MRI-negative patients, indicating effective targeting of MRI-positive lesions.

Indexed as

Biochemical failureMultiparametric MRIProstate cancerRadical prostatectomySalvage radiotherapy

Identifiers

PMID31452628
PMCPMC6700415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.