ArticleThe Canadian journal of hospital pharmacy
Hospital Pharmacists' Perceptions and Decision-Making Related to Drug-Drug Interactions.
Article in The Canadian journal of hospital pharmacy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gaps in the detection of drug-drug interactions between antipsychotic and cardiometabolic medications: a multisource analysis.BMC medicine · 2025Pooled it
- Impact of medication nonadherence and drug-drug interaction testing on the management of primary care patients with polypharmacy: a randomized controlled trial.BMC medicine · 2024Trial
- Standardizing and Comparing Management Recommendations for Potential Drug-Drug Interactions Across Different Interaction Checkers.Drug safety · 2026Article
- How to manage the overwhelming amount of database-detected interactions? A focus group meeting study on the management of database-detected risks of drug interactions.European journal of hospital pharmacy : science and practice · 2026Article
- Prevalence and Duration of Potential Drug-Drug Interactions Among US Nursing Home Residents, 2018-2020.Journal of the American Geriatrics Society · 2025Article
- Factors Influencing Health Care Professionals' Perceptions of Frequent Drug-Drug Interaction Alerts.ACI open · 2024Article
- CancelRx case study: implications for clinic and community pharmacy work systems.BMC health services research · 2023Article
- Cognitive task analysis of clinicians' drug-drug interaction management during patient care and implications for alert design.BMJ open · 2023Article
- Potential Drug Interactions in Adults Living in Manaus: A Real-World Comparison of Two Databases, 2019.Turkish journal of pharmaceutical sciences · 2022Article
- CancelRx implementation: Observed changes to medication discontinuation workflows over time.Exploratory research in clinical and social pharmacy · 2022Article
- TLC-Act: A Novel Tool for Managing Drug Interactions.The Canadian journal of hospital pharmacy · 2022Article
- Ambulatory Heart Function and Transplant Patients' Perceptions of Drug-Drug Interactions: A Qualitative Study.The Canadian journal of hospital pharmacy · 2022Article
- Pharmacists' perceptions of a machine learning model for the identification of atypical medication orders.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- Assessment of Physician's Knowledge of Potential Drug-Drug Interactions: An Online Survey in China.Frontiers in medicine · 2021Article
- Comparison of Clinical Importance of Drug Interactions Identified by Hospital Pharmacists and a Local Clinical Decision Support System.The Canadian journal of hospital pharmacy · 2021Article
- Clinical Decision Support and Implications for the Clinician Burnout Crisis.Yearbook of medical informatics · 2020Review
- Community pharmacist perceptions of drug-drug interactions.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPCArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPharmacists often overlook drug interaction alerts because of limitations in clinical decision support (CDS) software systems intended to detect evidence-based, clinically significant drug-drug interactions (DDIs). Alert fatigue, which occurs when pharmacists become desensitized to an overload of DDIs, may also contribute.
objectivesTo gain a better understanding of how pharmacists assess common DDIs and the extent to which computerized drug alerts affect their decision-making, as background for initiatives to overcome alert fatigue and improve detection of DDIs.
methodsThis qualitative study used focus group methodology. A structured focus group was planned at each of 3 large tertiary hospitals. Pharmacists were invited to participate if their jobs included patient care and/or dispensary responsibilities. The focus group discussions were audio-recorded and subsequently transcribed, analyzed, and coded into themes using NVivo software. Four main categories of themes were identified: perceived challenges, pharmacists' assessment of DDIs, barriers to responding to alerts, and proposed solutions.
resultsThe participants (
conclusionsAlthough alert fatigue was reported to be a common factor responsible for pharmacists missing DDIs, other barriers also exist. Participants suggested ways to limit DDI alerts to those that are clinically relevant. Having a collaborative team of pharmacists periodically review the DDIs embedded in the CDS system, incorporating a colour-code system, and removing duplicate entries were discussed as ways to improve system efficiency.
Indexed as
Identifiers
31452540PMC6699872What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.