Evidence map›Paper›PMID 31452457›Full record

ArticleMolecular pain

Endoplasmic reticulum stress promoting caspase signaling pathway-dependent apoptosis contributes to bone cancer pain in the spinal dorsal horn.

Qiuli He, Tingting Wang, Huadong Ni, Qianying Liu, Kang An, Jiachun Tao, Yajing Chen, Longsheng Xu, Chunyan Zhu, Ming Yao

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

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  12. Anticarcinogenic Effects of Isothiocyanates on Hepatocellular Carcinoma.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Qiuli HeDepartment of Anesthesiology, Bengbu Medical College, Bengbu, China.
Tingting WangDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Huadong NiDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Qianying LiuDepartment of Anesthesiology, Bengbu Medical College, Bengbu, China.
Kang AnDepartment of Anesthesiology, Affliated Drum Tower Hospital of Medical School of Nanjing University, Nanjing, China.
Jiachun TaoDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Yajing ChenDepartment of Anesthesiology, Bengbu Medical College, Bengbu, China.
Longsheng XuDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Chunyan ZhuDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Ming YaoDepartment of Anesthesiology and Pain Research Center, The First Affiliated Hospital of Jiaxing University, Jiaxing, China.ORCID 0000-0002-4226-8473
Jiaxing University · CNBengbu Medical College · CNZhejiang Chinese Medical University · CNNanjing Drum Tower Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Activating Transcription Factor 6AnimalsApoptosisBlotting, WesternBone NeoplasmsCancer PainCaspase 3CaspasesEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressFemaleHeat-Shock ProteinsMembrane ProteinsPhosphorylationProtein Serine-Threonine KinasesRatsActivating Transcription Factor 6Atf6 protein, ratCaspase 3CaspasesEndoplasmic Reticulum Chaperone BiPErn2 protein, ratGRP78 protein, ratHeat-Shock ProteinsMembrane ProteinsProtein Serine-Threonine KinasesThapsigarginapoptosisbone cancer paincaspase-3aEndoplasmic reticulum stress

Identifiers

PMID31452457
PMCPMC6767730
OpenAlexW2970543928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.