Evidence map›Paper›PMID 31452244›Full record

ArticleMagnetic resonance in medicine2020

Natively fat-suppressed 5D whole-heart MRI with a radial free-running fast-interrupted steady-state (FISS) sequence at 1.5T and 3T.

Jessica A M Bastiaansen, Davide Piccini, Lorenzo Di Sopra, Christopher W Roy, John Heerfordt, Robert R Edelman, Ioannis Koktzoglou, Jérôme Yerly, Matthias Stuber

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07613398 (Assessment and Validation of the Established Free-Running Framework for Cardiac Function by Magnetic Resonance Imaging), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07613398 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessment and Validation of the Established Free-Running Framework for Cardiac Function by Magnetic Resonance Imaging (FAST-CMR): An International Multi-Center, Multi-Vendor Study at 1.5T

Typeobservational_patient_registrySponsorMatthias StuberRan2026 to 2030Enrolled300ConditionsCongenital Heart Diseases, Cardiac Diseases
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
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  8. Article
  9. Review
  10. Combined free-running four-dimensional anatomical and flow magnetic resonance imaging with native contrast using Synchronization of Neighboring Acquisitions by Physiological Signals.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Article
  11. Trajectory correction enables free-running chemical shift encoded imaging for accurate cardiac proton-density fat fraction quantification at 3T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024 · on this map
    Article
  12. Golden-Angle Radial MRI: Basics, Advances, and Applications.Journal of magnetic resonance imaging : JMRI · 2022
    Review
  13. Free-running cardiac and respiratory motion-resolved 5D whole-heart coronary cardiovascular magnetic resonance angiography in pediatric cardiac patients using ferumoxytol.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  14. Article
  15. Article
  16. Long-term prognostic value of whole-heart coronary magnetic resonance angiography.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  17. Motion compensated whole-heart coronary cardiovascular magnetic resonance angiography using focused navigation (fNAV).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  18. Article
  19. Review
  20. Isotropic three-dimensional cardiac cine imaging at 0.55T using stack-of-spiral sampling and four-dimensional iterative motion compensation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jessica A M BastiaansenDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-5485-1308
Davide PicciniDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-4663-3244
Lorenzo Di SopraDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-3426-9457
Christopher W RoyDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
John HeerfordtDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-6837-4733
Robert R EdelmanDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.ORCID 0000-0002-0013-8822
Ioannis KoktzoglouDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois.
Jérôme YerlyDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Matthias StuberDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-9843-2028
University of Lausanne · CHCentre d'Imagerie BioMedicale · CHSiemens (Switzerland) · CHNorthShore University HealthSystem · USNorthwestern University · US

Funding

Nonenhanced 3T QISS MR Angiography of the Peripheral ArteriesR01HL130093 · NHLBI · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI EDELMAN, ROBERT R. · 2016 to 2019
$2.0M
Rapid Real-Time MR Angiography of Suspected StrokeR01EB027475 · NIBIB · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI KOKTZOGLOU, IOANNIS · 2018 to 2021
$1.9M
Pre-Procedural Evaluation of High-Risk Patients using Next-Generation Radial QISSR01HL137920 · NHLBI · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI EDELMAN, ROBERT R. · 2018 to 2021
$1.5M
NHLBI NIH HHS R01 HL130093NHLBI NIH HHS R01 HL137920NIBIB NIH HHS R01 EB027475
6 · The paper itself

Abstract

purposeTo implement, optimize, and test fast interrupted steady-state (FISS) for natively fat-suppressed free-running 5D whole-heart MRI at 1.5 tesla (T) and 3T.

methodsFISS was implemented for fully self-gated free-running cardiac- and respiratory-motion-resolved radial imaging of the heart at 1.5T and 3T. Numerical simulations and phantom scans were performed to compare fat suppression characteristics and to determine parameter ranges (number of readouts [NR] per FISS module and TR) for effective fat suppression. Subsequently, free-running FISS data were collected in 10 healthy volunteers and images were reconstructed with compressed sensing. All acquisitions were compared with a continuous balanced steady-state free precession version of the same sequence, and both fat suppression and scan times were analyzed.

resultsSimulations demonstrate a variable width and location of suppression bands in FISS that were dependent on TR and NR. For a fat suppression bandwidth of 100 Hz and NR ≤ 8, simulations demonstrated that a TR between 2.2 ms and 3.0 ms is required at 1.5T, whereas a range of 3.0 ms to 3.5 ms applies at 3T. Fat signal increases with NR. These findings were corroborated in phantom experiments. In volunteers, fat SNR was significantly decreased using FISS compared with balanced steady-state free precession (P < 0.05) at both field strengths. After protocol optimization, high-resolution (1.1 mm

conclusionAn optimal FISS parameter range was determined enabling natively fat-suppressed 5D whole-heart free-running MRI with a single continuous scan at 1.5T and 3T, demonstrating potential for cardiac imaging and noncontrast angiography.

Indexed as

Free RadicalsMagnetic Resonance ImagingRespiratory-Gated Imaging TechniquesAlgorithmsComputer SimulationCoronary AngiographyElectrocardiographyHealthy VolunteersHeartHumansImage Processing, Computer-AssistedModels, TheoreticalMotionNormal DistributionPhantoms, ImagingSignal-To-Noise RatioFree Radicals1.5T MRI3D radial3T MRIbSSFPcompressed sensingfat suppressionFISSfree-runningnoncontrastwhole-heart MRI

Identifiers

PMID31452244
PMCPMC6778714
OpenAlexW2970738661

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.