Evidence map›Paper›PMID 31452048›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2020

Sleep and pain: recent insights, mechanisms, and future directions in the investigation of this relationship.

Alberto Herrero Babiloni, Beatrice P De Koninck, Gabrielle Beetz, Louis De Beaumont, Marc O Martel, Gilles J Lavigne

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alberto Herrero BabiloniResearch Center, Hôpital Du Sacré-Coeur de Montréal, CIUSSS Du Nord-de-l'Île-de-Montréal, Université De Montréal, Montreal, Canada. herre220@umn.edu.ORCID http://orcid.org/0000-0001-5588-5916
Beatrice P De KoninckResearch Center, Hôpital Du Sacré-Coeur de Montréal, CIUSSS Du Nord-de-l'Île-de-Montréal, Université De Montréal, Montreal, Canada.
Gabrielle BeetzResearch Center, Hôpital Du Sacré-Coeur de Montréal, CIUSSS Du Nord-de-l'Île-de-Montréal, Université De Montréal, Montreal, Canada.
Louis De BeaumontResearch Center, Hôpital Du Sacré-Coeur de Montréal, CIUSSS Du Nord-de-l'Île-de-Montréal, Université De Montréal, Montreal, Canada.
Marc O MartelExperimental Medicine Division, McGill University, Montreal, Canada.
Gilles J LavigneResearch Center, Hôpital Du Sacré-Coeur de Montréal, CIUSSS Du Nord-de-l'Île-de-Montréal, Université De Montréal, Montreal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disturbances and chronic pain are considered public health concerns. They are frequently associated, and the direction of its relationship and possible mechanisms underlying it are frequently debated. The exploration of the sleep-pain association is of great clinical interest to explore in order to steer potential therapeutic avenues, accommodate the patient's experience, and adapt the common practice of health professionals. In this review, the direction between sleep-pain in adult and pediatric populations will be discussed. Moreover, the possible mechanisms contributing to this relationship as endogenous pain modulation, inflammation, affect, mood and other states, the role of different endogenous substances (dopamine, orexin, melatonin, vitamin D) as well as other lesser known such as cyclic alternating pattern among others, will be explored. Finally, directions for future studies on this area will be discussed, opening up to the addition of tools such as brain imaging (e.g., fMRI), electrophysiology and non-invasive brain stimulation techniques. Such resources paired with artificial intelligence are key to personalized medicine management for patients facing pain and sleep interacting conditions.

Indexed as

Affective SymptomsChronic PainInflammationSleep Wake DisordersAdultChildHumansChronic painInsomniaObstructive sleep apneaPain modulationSleep disturbance

Identifiers

PMID31452048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.