Evidence map›Paper›PMID 31451995›Full record

ArticleEuropean journal of epidemiology2019

Bias from self selection and loss to follow-up in prospective cohort studies.

Guido Biele, Kristin Gustavson, Nikolai Olavi Czajkowski, Roy Miodini Nilsen, Ted Reichborn-Kjennerud, Per Minor Magnus, Camilla Stoltenberg, Heidi Aase

Abstract read
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In one paragraph

Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guido BieleNorwegian Institute of Public Health, Oslo, Norway. guido.biele@fhi.no.ORCID http://orcid.org/0000-0002-4225-9024
Kristin GustavsonNorwegian Institute of Public Health, Oslo, Norway.
Nikolai Olavi CzajkowskiNorwegian Institute of Public Health, Oslo, Norway.
Roy Miodini NilsenNorwegian Institute of Public Health, Oslo, Norway.
Ted Reichborn-KjennerudNorwegian Institute of Public Health, Oslo, Norway.
Per Minor MagnusNorwegian Institute of Public Health, Oslo, Norway.
Camilla StoltenbergNorwegian Institute of Public Health, Oslo, Norway.
Heidi AaseNorwegian Institute of Public Health, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-selection into prospective cohort studies and loss to follow-up can cause biased exposure-outcome association estimates. Previous investigations illustrated that such biases can be small in large prospective cohort studies. The structural approach to selection bias shows that general statements about bias are not possible for studies that investigate multiple exposures and outcomes, and that inverse probability of participation weighting (IPPW) but not adjustment for participation predictors generally reduces bias from self-selection and loss to follow-up. We propose to substantiate assumptions in structural models of selection bias through calculation of genetic correlations coefficients between participation predictors, outcome, and exposure, and to estimate a lower bound for bias due to self-selection and loss to follow-up by comparing effect estimates from IPP weighted and unweighted analyses. This study used data from the Norwegian Mother and Child Cohort Study and the Medical Birth Registry of Norway. Using the example of risk factors for ADHD, we find that genetic correlations between participation predictors, exposures, and outcome suggest the presence of bias. The comparison of exposure-outcome associations from regressions with and without IPPW revealed meaningful deviations. Assessment of selection bias for entire multi-exposure multi-outcome cohort studies is not possible. Instead, it has to be assessed and controlled on a case-by-case basis.

Indexed as

Selection BiasBiasChild Development Disorders, PervasiveCohort StudiesFemaleFollow-Up StudiesHumansMaleNorwayPregnancyPrenatal Exposure Delayed EffectsProspective StudiesRisk FactorsADHDBayesian estimationBiasCohort studyDirected acyclic graphsInverse probability weightingLoss to follow upSelf selection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.