Evidence map›Paper›PMID 31451936›Full record

ArticleNeurosurgical review2020

Association of maximum back and leg pain severity with objective functional impairment as assessed by five-repetition sit-to-stand testing: analysis of two prospective studies.

Victor E Staartjes, Anita M Klukowska, Marc L Schröder

2 registry-linked trialsOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03303300 completednot on this map

The Five-repetition Sit-to-stand Test as an Objective Measure of Functional Impairment in Patients With Lower Back Pain or Radiculopathy

TypeobservationalSponsorMarc SchröderRan2017 to 2017Enrolled237ConditionsDegenerative Disc Disease, Degenerative Spondylolisthesis, Herniated Disc, Stenosis, Spinal
NCT03321357 completednot on this map

Test-retest-reliability and At-home-assessment Feasibility of the Five-repetition Sit-to-stand Test (5R-STS)

TypeobservationalSponsorBergman ClinicsRan2017 to 2018Enrolled100ConditionsDegenerative Disc Disease, Spondylolisthesis, Spondylosis, Herniated Nucleus PulposusArmsfive-repetition sit-to-stand test
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The reliability and validity of the 30-second chair sit-to-stand test and the five-repetition sit-to-stand test in individuals following lumbar spinal surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Clinical and biomechanical biomarkers of altered functional transitions in lumbar spinal stenosis with neurogenic claudication.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Victor E StaartjesDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, The Netherlands. victor.staartjes@gmail.com.ORCID http://orcid.org/0000-0003-1039-2098
Anita M KlukowskaDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, The Netherlands.
Marc L SchröderDepartment of Neurosurgery, Bergman Clinics, Naarden, Rijksweg 69, 1411 GE, Naarden, The Netherlands.
Bergman Clinics · NLUniversity Hospital of Zurich · CHUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The five-repetition sit-to-stand (5R-STS) test was designed to capture objective functional impairment (OFI), and provides a new adjunctive dimension in patient assessment. Its interpretability and confounders remain poorly understood. We quantify the association among maximum patient-reported back (MBP) or leg pain (MLP) and OFI as measured by the 5R-STS using data from two prospective studies. Patients performed the 5R-STS test and completed visual analogue scales (VAS) for back and leg pain severity. Maximum pain severity was defined as VAS scores of 9 or 10. The association of MBP and MLP with 5R-STS test times as well as with the presence of OFI (> 10.5 s) and severe OFI (> 22.0 s) as determined by the 5R-STS baseline severity stratification was quantified by use of crude and adjusted regression models. A total of 258 patients were included. MBP and MLP were reported by 27 (10.5%) and 76 (29.5%) patients, respectively. Rates of OFI differed among patients with (92.6%) and without (55.0%) MBP (p < 0.001), while presence of MLP did not influence OFI (61.8% vs. 57.7%, p = 0.632). Similarly, severe OFI was more common among patients with MBP (33.3% vs. 9.1%, p < 0.001), but not among patients with MLP (17.1% vs. 9.3%, p = 0.119). In the adjusted logistic analysis, the influence of MBP on OFI persisted (odds ratio [OR] 10.08, confidence interval [CI] 2.73-65.74, p = 0.003), while MLP demonstrated no association (OR 0.91, CI 0.49-1.72, p = 0.780). These associations were consistent with findings pertaining to raw 5R-STS test times and in discectomy patients alone. There is a strong association of maximum back pain severity on VAS with the degree of OFI determined by 5R-STS testing. Radiculopathy with maximally strong back pain, however, does not seem to relevantly influence 5R-STS performance.Trial registration ClinicalTrials.gov : NCT03321357 & NCT03303300.

Indexed as

LegAdultAgedBack PainDiskectomyFemaleHumansIntervertebral Disc DegenerationMaleMiddle AgedPainPain MeasurementProspective StudiesRegression AnalysisSitting PositionSpinal StenosisDegenerative disc diseaseFunctional impairmentLumbar disc herniationLumbar spinal stenosisObjective functional testingPain

Identifiers

PMID31451936
OpenAlexW2970271119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.