Evidence map›Paper›PMID 31451696›Full record

ArticleNature communications2019

Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.

Nicole Marquardt, Eliisa Kekäläinen, Puran Chen, Magda Lourda, Jennifer N Wilson, Marlena Scharenberg, Per Bergman, Mamdoh Al-Ameri, Joanna Hård, Jeffrey E Mold and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 147 citations in OpenAlex.

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  17. Multi-omics and Mendelian randomization identifyTranslational lung cancer research · 2025
    Article
  18. Review
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nicole MarquardtCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. nicole.marquardt@ki.se.ORCID http://orcid.org/0000-0003-3186-4752
Eliisa KekäläinenCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Puran ChenCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Magda LourdaCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-3155-1123
Jennifer N WilsonCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-4599-0311
Marlena ScharenbergCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-7659-7216
Per BergmanThoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Mamdoh Al-AmeriThoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Joanna HårdDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Jeffrey E MoldDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Hans-Gustaf LjunggrenCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Jakob MichaëlssonCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human lung tissue-resident NK cells (trNK cells) are likely to play an important role in host responses towards viral infections, inflammatory conditions and cancer. However, detailed insights into these cells are still largely lacking. Here we show, using RNA sequencing and flow cytometry-based analyses, that subsets of human lung CD69

Indexed as

Immunity, MucosalAgedAged, 80 and overBone Marrow CellsCD8-Positive T-LymphocytesDatasets as TopicFemaleHumansKiller Cells, NaturalLungLung DiseasesMaleMiddle AgedPneumonectomyRespiratory MucosaRNA-Seq

Identifiers

PMID31451696
PMCPMC6710242
OpenAlexW2971066179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.