Evidence map›Paper›PMID 31451650›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin.

Jason Hill, Erik D Enbody, Mats E Pettersson, C Grace Sprehn, Dorte Bekkevold, Arild Folkvord, Linda Laikre, Gunnar Kleinau, Patrick Scheerer, Leif Andersson

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. The genetic foundations of convergent traits.Nature reviews. Genetics · 2026
    Review
  3. Sperm, egg, and embryo proteins critical for genetic adaptation of herring to low salinity in the Baltic Sea.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Jason HillDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Erik D EnbodyDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Mats E PetterssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
C Grace SprehnDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Dorte BekkevoldNational Institute of Aquatic Resources, Technical University of Denmark, 8600 Silkeborg, Denmark.ORCID 0000-0002-5297-032X
Arild FolkvordDepartment of Biological Sciences, University of Bergen, 5020 Bergen, Norway.ORCID 0000-0002-4763-0590
Linda LaikreDepartment of Zoology, Division of Population Genetics, Stockholm University, SE-106 91 Stockholm, Sweden.
Gunnar KleinauGroup Protein X-ray Crystallography and Signal Transduction, Institute of Medical Physics and Biophysics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, D-10117 Berlin, Germany.
Patrick ScheererGroup Protein X-ray Crystallography and Signal Transduction, Institute of Medical Physics and Biophysics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, D-10117 Berlin, Germany.
Leif AnderssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; leif.andersson@imbim.uu.se.ORCID 0000-0002-4085-6968
Uppsala University · SEHumboldt-Universität zu Berlin · DENorwegian Institute of Marine Research · NOStockholm University · SETechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolutionary process that occurs when a species colonizes a new environment provides an opportunity to explore the mechanisms underlying genetic adaptation, which is essential knowledge for understanding evolution and the maintenance of biodiversity. Atlantic herring has an estimated total breeding stock of about 1 trillion (10

Indexed as

Evolution, MolecularAdaptation, BiologicalAmino Acid SubstitutionAnimalsFishesFish ProteinsGenetic LociPhenylalanineProtein Conformation, alpha-HelicalRhodopsinSelection, GeneticSequence Homology, Amino AcidStructure-Activity RelationshipTyrosineVision, OcularWhole Genome SequencingFish ProteinsPhenylalanineRhodopsinTyrosineadaptationconvergent evolutionnatural selectionselective sweep

Identifiers

PMID31451650
PMCPMC6744887
OpenAlexW2970872048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.