Evidence map›Paper›PMID 31451543›Full record

ArticleJournal of bacteriology2019

PQS Produced by the Pseudomonas aeruginosa Stress Response Repels Swarms Away from Bacteriophage and Antibiotics.

Jean-Louis Bru, Brandon Rawson, Calvin Trinh, Katrine Whiteson, Nina Molin Høyland-Kroghsbo, Albert Siryaporn

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 83 citations in OpenAlex.

  1. α-Mangostin attenuatesVirulence · 2026
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  7. Factors governing the response ofFrontiers in cellular and infection microbiology · 2026
    Review
  8. Essential role of cytochromeFrontiers in cellular and infection microbiology · 2026
    Article
  9. Article
  10. Phage-host interaction inApplied and environmental microbiology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. PQS and pyochelin inMicrobiology spectrum · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jean-Louis BruDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Brandon RawsonDepartment of Physics & Astronomy, University of California, Irvine, California, USA.
Calvin TrinhSchool of Biological Sciences, University of California, Irvine, California, USA.
Katrine WhitesonDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.ORCID 0000-0002-5423-6014
Nina Molin Høyland-KroghsboDepartment of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark nmhk@sund.ku.dk asirya@uci.edu.ORCID 0000-0001-5904-8859
Albert SiryapornDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA nmhk@sund.ku.dk asirya@uci.edu.
University of California, Irvine · USUniversity of Copenhagen · DK

Funding

Real-time metabolic analysis of virulence activation in P. aeruginosa using fluorescence lifetime imaging microscopy (FLIM)R21AI139968 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SIRYAPORN, ALBERT · 2019 to 2020
$382k
Role of mechanosensation in P. aeruginosa virulence and colonizationK22AI112816 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SIRYAPORN, ALBERT · 2016 to 2017
$265k
NIAID NIH HHS K22 AI112816NIAID NIH HHS R21 AI139968
6 · The paper itself

Abstract

We investigate the effect of bacteriophage infection and antibiotic treatment on the coordination of swarming, a collective form of flagellum- and pilus-mediated motility in bacteria. We show that phage infection of the opportunistic bacterial pathogen

Indexed as

Anti-Bacterial AgentsFimbriae, BacterialFlagellaMicrobial ViabilityMovementPseudomonas aeruginosaPseudomonas PhagesQuinolonesQuorum SensingSignal TransductionStress, Physiological2-heptyl-3-hydroxy-4-quinoloneAnti-Bacterial AgentsQuinolonesantibioticsbacteriophagequorum sensingstress responseswarming

Identifiers

PMID31451543
PMCPMC6832071
OpenAlexW2970323266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.