Evidence map›Paper›PMID 31451505›Full record

ArticleAntimicrobial agents and chemotherapy2019

CreC Sensor Kinase Activation Enhances Growth of Escherichia coli in the Presence of Cephalosporins and Carbapenems.

Yuiko Takebayashi, Emma S Taylor, Sam Whitwam, Matthew B Avison

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuiko TakebayashiSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Emma S TaylorSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Sam WhitwamSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Matthew B AvisonSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom matthewb.avison@bris.ac.uk.ORCID 0000-0003-1454-8440
University of Bristol · GB

Funding

Biotechnology and Biological Sciences Research Council BB/C514266/1Medical Research Council MR/N013646/1
6 · The paper itself

Abstract

Mutants with enhanced growth in the presence of an antibiotic are more difficult to identify than mutants where the antibiotic's MIC increases, because they are not amenable to lethal selection

Indexed as

Anti-Bacterial Agentsbeta-LactamasesCarbapenemsCefoxitinCephalosporinsEscherichia coliEscherichia coli ProteinsMicrobial Sensitivity TestsProtein KinasesRegulonAnti-Bacterial Agentsbeta-LactamasesCarbapenemsCefoxitinCephalosporinsCreC protein, E coliEscherichia coli ProteinsProtein Kinasesfitnesstolerancetwo-component system

Identifiers

PMID31451505
PMCPMC6811401
OpenAlexW2970323845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.