Evidence map›Paper›PMID 31451496›Full record

ArticleAntimicrobial agents and chemotherapy2019

Designed Antimicrobial Peptides for Recurrent Vulvovaginal Candidiasis Treatment.

Kathryn W Woodburn, L Edward Clemens, Jesse Jaynes, Lydia-Marie Joubert, Alfred Botha, Hasan Nazik, David A Stevens

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  12. Immunomodulatory and Allergenic Properties of Antimicrobial Peptides.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Article
  15. Changes in the Ultrastructure ofMicroorganisms · 2020
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kathryn W WoodburnRiptide Bioscience, Inc., Vallejo, California, USA kathryn.w.woodburn@gmail.com.
L Edward ClemensRiptide Bioscience, Inc., Vallejo, California, USA.
Jesse JaynesIntegrative Biosciences, College of Agriculture, Environment and Nutrition Sciences, Tuskegee University, Tuskegee, Alabama, USA.
Lydia-Marie JoubertMicrobiology Department, Stellenbosch University, Stellenbosch, South Africa.
Alfred BothaMicrobiology Department, Stellenbosch University, Stellenbosch, South Africa.
Hasan NazikCalifornia Institute for Medical Research, San Jose, California, USA.
David A StevensCalifornia Institute for Medical Research, San Jose, California, USA.
Stellenbosch University · ZACalifornia Institute for Medical Research · USStanford University · USTuskegee University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent vulvovaginal candidiasis (RVVC) is a widespread chronic infection that has a substantial negative impact on work and quality of life. The development of antimicrobial resistance and biofilm formation are speculated to contribute to

Indexed as

AnimalsAntifungal AgentsAntimicrobial Cationic PeptidesBiofilmsCandidaCandidiasis, VulvovaginalCell SurvivalDrug Resistance, FungalFemaleFluconazoleHumansKeratinocytesMicrobial Sensitivity TestsPeptidesRatsRats, WistarAntifungal AgentsAntimicrobial Cationic PeptidesFluconazolePeptidesantifungal activityantifungalsantimicrobial peptidesbiofilmfungicidal activityvulvovaginal candidiasis

Identifiers

PMID31451496
PMCPMC6811422
OpenAlexW2969777679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.