Evidence map›Paper›PMID 31451492›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Prospective Comparison of PET Imaging with PSMA-Targeted

Steven P Rowe, Xin Li, Bruce J Trock, Rudolf A Werner, Sarah Frey, Michael DiGianvittorio, J Keith Bleiler, Diane K Reyes, Rehab Abdallah, Kenneth J Pienta and 2 more

Open access · bronzeAbstract readClinical TrialComparative Study
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. The performance ofAsian journal of andrology
    Pooled it
  2. Radiology · 2022
    Trial
  3. Review
  4. Review
  5. Article
  6. Prospective Head-to-Head Comparison ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  7. Article
  8. Article
  9. Molecular imaging of bone metastasis.Journal of bone oncology · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. A Comparison ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  15. Translating a radiolabeled imaging agent to the clinic.Advanced drug delivery reviews · 2022
    Review
  16. Article
  17. Enzymatic synthesis of fluorinated compounds.Applied microbiology and biotechnology · 2021
    Review
  18. Piflufolastat F 18: Diagnostic First Approval.Molecular diagnosis & therapy · 2021
    Review
  19. European journal of nuclear medicine and molecular imaging · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Steven P RoweRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland srowe8@jhmi.edu.
Xin LiRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Bruce J TrockJames Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Rudolf A WernerRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sarah FreyRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Michael DiGianvittorioRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
J Keith BleilerGreater Boston Urology, Dedham, Massachusetts.
Diane K ReyesJames Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Rehab AbdallahRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Kenneth J PientaJames Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Michael A GorinRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Martin G PomperRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Johns Hopkins University · USBoston University · USJohns Hopkins Medicine · USSpectrum Research (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastases in prostate cancer (PCa) have important prognostic significance, and imaging modalities used for PCa staging should have high sensitivity for detecting such lesions. Prostate-specific membrane antigen (PSMA)-targeted PET radiotracers are promising new agents for imaging PCa. We undertook a head-to-head comparison of PSMA-targeted 2-(3-{1-carboxy-5-[(6-

Indexed as

Sodium FluorideAntigens, SurfaceBone NeoplasmsFluorine RadioisotopesGlutamate Carboxypeptidase IIHumansLysineMalePositron Emission Tomography Computed TomographyProspective StudiesProstatic NeoplasmsUrea2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acidAntigens, SurfaceFluorine-18Fluorine RadioisotopesFOLH1 protein, humanGlutamate Carboxypeptidase IILysineSodium FluorideUrea18FNabone metastasesPET/CTprostate cancerprostate-specific membrane antigenPSMAPyL

Identifiers

PMID31451492
PMCPMC8801956
OpenAlexW2970721873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.