Evidence map›Paper›PMID 31451439›Full record

ReviewJournal of geriatric oncology2020

Arti Hurria and the progress in integrating the geriatric assessment into oncology: Young International Society of Geriatric Oncology review paper.

Clark DuMontier, Mina S Sedrak, Wee Kheng Soo, Cindy Kenis, Grant R Williams, Kristen Haase, Magnus Harneshaug, Hira Mian, Kah Poh Loh, Siri Rostoft and 2 more

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of geriatric oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05432726 (Prediction of Chemotherapy Toxicity and Survival in Elderly Cancer Patients by Using CARG Score), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05432726 unknown statusnot on this mapstarted 2022, after this paper: background citation

Prediction of Chemotherapy Toxicity and Survival in Elderly Cancer Patients by Using CARG Score (Cancer and Aging Research Group Score)

TypeobservationalSponsorAssiut UniversityRan2022 to 2025Enrolled63ConditionsSolid Tumors ,AdultsArmscalculating CARG score
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Nurse Practitioners' Experiences Navigating Treatment Decision-Making Affecting Older People with Neurocognitive Disorders and Cancer.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Pain among older adults with gastrointestinal malignancies- results from the cancer and aging resilience evaluation (CARE) Registry.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. The missing voice in multidisciplinary tumor boards.Journal of geriatric oncology · 2021
    Article
  17. Surgical Considerations for Older Adults With Cancer: A Multidimensional, Multiphase Pathway to Improve Care.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Review
  18. Article
  19. Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.Journal of the National Cancer Institute · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 5 countries.

Clark DuMontierBrigham and Women's Hospital, Marcus Institute for Aging Research, Harvard Medical School, Boston, MA, United States of America. Electronic address: cdumontier@partners.org.
Mina S SedrakCity of Hope Comprehensive Cancer Center, Duarte, CA, United States of America.
Wee Kheng SooEastern Health Clinical School, Monash University, 5 Arnold St, Box Hill, VIC, Australia; Department of Aged Medicine, Eastern Health, 8 Arnold St, Box Hill, VIC, Australia; Department of Cancer Services, Eastern Health, 8 Arnold St, Box Hill, VIC, Australia.
Cindy KenisDepartment of General Medical Oncology and Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium.
Grant R WilliamsDivision of Hematology/Oncology, Geriatrics, and Palliative Care, Institute of Cancer Outcomes and Survivorship, O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, UK.
Kristen HaaseCollege of Nursing, University of Saskatchewan, 104 Clinic Place, Saskatoon, Canada.
Magnus HarneshaugThe Research Centre for Age Related Functional Decline and Diseases, Innlandet Hospital Trust, P.O. box 68, 2313 Ottestad, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, P.O. box 4956, Nydalen, 0424 Oslo, Norway.
Hira MianJuravinski Cancer Center, Department of Oncology, McMaster University, Hamilton, ON, Canada.
Kah Poh LohJames P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY, USA.
Siri RostoftInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
William DaleCity of Hope Comprehensive Cancer Center, Duarte, CA, United States of America.
Harvey Jay CohenCenter for the Study of Aging and Human Development, Duke University, Durham, NC, United States of America.
City of Hope · USDuke University · USEastern Health · AUHarvard University · USInnlandet Hospital Trust · NOKU Leuven · BEMcMaster University · CAOslo University Hospital · NOUniversity of Alabama at Birmingham · USUniversity of Rochester Medical Center · USUniversity of Saskatchewan · CA

Funding

Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with CancerK24AG055693 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE · 2018 to 2026
$1.4M
Geriatric Oncology: Educating nurses to improve quality careR25CA183723 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI DALE, WILLIAM, LOSCALZO, MATTHEW JOSEPH · 2015 to 2019
$1.3M
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults with Colorectal Cancer: The M&M StudyK08CA234225 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, GRANT R · 2018 to 2022
$1.0M
Geriatric Oncology Research Infrastructure to Improve Clinical CareR21AG059206 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI DALE, WILLIAM, MOHILE, SUPRIYA G. · 2018 to 2019
$478k
Geriatric Oncology Research to Improve Clinical CareU13AG038151 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI HURRIA, ARTI · 2010 to 2014
$228k
NCI NIH HHS K08 CA234225NCI NIH HHS R25 CA183723NIA NIH HHS K24 AG055693NIA NIH HHS R21 AG059206NIA NIH HHS T32 AG023480NIA NIH HHS U13 AG038151
6 · The paper itself

Abstract

Until recently, the progress in the diagnosis and management of cancer has not been matched by similar progress in the assessment of the increasing numbers of older and more complex patients with cancer. Dr. Arti Hurria identified this gap at the outset of her career, which she dedicated toward studying the geriatric assessment (GA) as an improvement over traditional methods used in oncology to assess vulnerability in older patients with cancer. This review documents the progress of the GA and its integration into oncology. First, we detail the GA's origins in the field of geriatrics. Next, we chronicle the early rise of geriatric oncology, highlighting the calls of early thought-leaders to meet the demands of the rapidly aging cancer population. We describe Dr. Hurria's early efforts toward meeting these calls though the implementation of the GA in oncology research. We then summarize some of the seminal studies constituting the evidence base supporting GA's implementation. Finally, we lay out the evolution of cancer-focused guidelines recommending the GA, concluding with future needs to advance the next steps toward more widespread implementation in routine cancer care. Throughout, we describe Dr. Hurria's vision and its execution in driving progress of the GA in oncology, from her fellowship training to her co-authored guidelines recommending GA for all older adults with cancer-published in the year of her untimely death.

Indexed as

Geriatric AssessmentGeriatricsMedical OncologyNeoplasmsAgedHumansArti HurriaGeriatric assessmentGeriatric oncologyRisk stratificationSupportive careVulnerability

Identifiers

PMID31451439
PMCPMC7036024
OpenAlexW2969996881

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.