Evidence map›Paper›PMID 31451364›Full record

Trial reportPatient education and counseling2020

Randomized clinical trial of computerized PAINRelieveIt® for patients with sickle cell disease: PAINReportIt® and PAINUCope®.

Brenda W Dyal, Miriam O Ezenwa, Yingwei Yao, Robert E Molokie, Zaijie J Wang, Samir K Ballas, Marie L Suarez, Diana J Wilkie

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Patient education and counseling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Brenda W DyalUniversity of Florida, Department of Biobehavioral Nursing Science, Gainesville, FL, United States.
Miriam O EzenwaUniversity of Florida, Department of Biobehavioral Nursing Science, Gainesville, FL, United States; University of Illinois at Chicago College of Nursing, Department of Biobehavioral Health Science, Chicago, IL, United States; University of Illinois at Chicago Comprehensive Sickle Cell Center, Chicago, IL, United States.
Yingwei YaoUniversity of Florida, Department of Biobehavioral Nursing Science, Gainesville, FL, United States; University of Illinois at Chicago College of Nursing, Department of Biobehavioral Health Science, Chicago, IL, United States.
Robert E MolokieUniversity of Illinois at Chicago Comprehensive Sickle Cell Center, Chicago, IL, United States; University of Illinois at Chicago College of Medicine, Division of Hematology/Oncology, Chicago, IL, United States; Jesse Brown Veteran's Administration Medical Center, Chicago, IL, United States; University of Illinois at Chicago College of Pharmacy, Department of Biopharmaceutical Sciences and Comprehensive Sickle Cell Center Chicago, IL, United States.
Zaijie J WangUniversity of Illinois at Chicago College of Pharmacy, Department of Biopharmaceutical Sciences and Comprehensive Sickle Cell Center Chicago, IL, United States.
Samir K BallasThomas Jefferson University, Philadelphia, PA, United States.
Marie L SuarezUniversity of Illinois at Chicago College of Nursing, Department of Biobehavioral Health Science, Chicago, IL, United States.
Diana J WilkieUniversity of Florida, Department of Biobehavioral Nursing Science, Gainesville, FL, United States; University of Illinois at Chicago College of Nursing, Department of Biobehavioral Health Science, Chicago, IL, United States; University of Illinois at Chicago Comprehensive Sickle Cell Center, Chicago, IL, United States. Electronic address: diwilkie@ufl.edu.
University of Florida · USUniversity of Illinois Chicago · USThomas Jefferson University · US

Funding

Molecular mechanism and targeting of chronic pain in sickle cell diseaseR35HL140031 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WANG, ZAIJIE JIM · 2018 to 2024
$4.6M
Computerized PAINRelievelt for Adult Sickle Cell DiseaseR01HL078536 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WILKIE, DIANA J · 2006 to 2009
$3.1M
NHLBI NIH HHS R01 HL078536NHLBI NIH HHS R35 HL140031
6 · The paper itself

Abstract

objectiveTo compare effects of a tailored multimedia education program versus usual-care on barriers to pain management of adult patients with SCD.

methodsPretest/posttest randomized controlled trial (RCT) of 228 outpatients with SCD randomized to the tablet-based PAINUCope intervention focused on barriers to pain management, pain, and analgesic adherence or selection of games (control). Outcomes were barriers to pain management, pain, and analgesic adherence.

resultsThe barriers to pain management and pain scores did not change significantly from pretest to posttest for either condition. Changes in analgesic adherence rates from pretest to posttest were statistically significant for the intervention group (p = .046) but not for the usual care group (p = .419). The group difference was not statistically significant.

conclusionsThis first RCT of a tailored multimedia education intervention with adult patients with SCD did not significantly reduce the outcomes of interest compared to the control group. Findings provide insights for improving intervention delivery and reinforcement of patient behaviors. PRACTICE IMPLICATIONS: Study redesign is warranted with modifications that include theoretical and methodological approaches and patient-centered delivery of the intervention that take advantage of recent technology developments.

Indexed as

Anemia, Sickle CellAdultAnalgesicsHumansMultimediaPainPain ManagementAnalgesicsPain barriersPain managementPatient educationSickle cell disease

Identifiers

PMID31451364
PMCPMC6895421
OpenAlexW2969193668

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.