Evidence map›Paper›PMID 31450824›Full record

ArticleJournal of clinical medicine2019

Identification of a Shared Microbiomic and Metabolomic Profile in Systemic Autoimmune Diseases.

Chiara Bellocchi, Álvaro Fernández-Ochoa, Gaia Montanelli, Barbara Vigone, Alessandro Santaniello, Rosa Quirantes-Piné, Isabel Borrás-Linares, Maria Gerosa, Carolina Artusi, Roberta Gualtierotti and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Review
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  17. Review
  18. Insights into Microbiota in Sjögren's Syndrome.Medicina (Kaunas, Lithuania) · 2023
    Review
  19. Gut dysbiosis in autoimmune diseases: Association with mortality.Frontiers in cellular and infection microbiology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chiara BellocchiReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.
Álvaro Fernández-OchoaDepartment of Analytical Chemistry, University of Granada18016, Granada, Spain.
Gaia MontanelliReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.
Barbara VigoneReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.
Alessandro SantanielloReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.
Rosa Quirantes-PinéDepartment of Analytical Chemistry, University of Granada18016, Granada, Spain.
Isabel Borrás-LinaresDepartment of Analytical Chemistry, University of Granada18016, Granada, Spain.
Maria GerosaDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Carolina ArtusiDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Roberta GualtierottiDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Antonio Segura-CarretteroDepartment of Analytical Chemistry, University of Granada18016, Granada, Spain.
Marta E Alarcón-RiquelmeCentre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, 18016 Granada, Spain.
Lorenzo BerettaReferral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy. lorenzo.beretta@policlinico.mi.it.

Funding

EU/EFPIA/Innovative Medicines Initiative Joint Undertaking PRECISESADS 115565
6 · The paper itself

Abstract

Dysbiosis has been described in systemic autoimmune diseases (SADs), including systemic lupus erythematosus (SLE), Sjögren's syndrome (SjS), and primary anti-phosholipid syndrome (PAPS), however the biological implications of these associations are often elusive. Stool and plasma samples from 114 subjects, including in SLE (

Indexed as

metabolomicsmicrobiomicprimary anti-phosholipid syndromeSjögren’s syndromesystemic autoimmune diseasessystemic lupus erythematosusundifferentiated connective tissue diseases

Identifiers

PMID31450824
PMCPMC6780636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.